| 301. | Try Not To Be Amazed | Part 2 | Zach King Reaction | AyChristene Reacts | 271 | |
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| 302. | Yanderes Need To Love | Yanderedev Reaction | AyChristene Reacts | 271 | | Yandere Simulator
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| 303. | Yandere Meme Compilation | Renji Reaction | AyChristene Reacts | 271 | |
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| 304. | NEW ISLAND WHO DIS? | ANIMAL CROSSING NEW HORIZONS GAMEPLAY | 271 | | Animal Crossing: New Horizons
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| 305. | 50k Subscriber Milestone | All Because Of You Music Video | AyChristene Sings | 270 | |
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| 306. | ANNOYING STUDENT COUNCIL | YANDERE SIMULATOR GAMEPLAY | 270 | | Yandere Simulator
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| 307. | Sister Location | Part 3 | Beat Night 2 | PC Gameplay | 270 | | Five Nights at Freddy's: Sister Location
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| 308. | DOKI DOKI LITERATURE CLUB Gameplay Part 1 | 270 | | Doki Doki Literature Club!
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| 309. | Yandere Meme Compilation | Part 5 | Try Not To Laugh | AyChristene Reacts | 267 | | Yandere Simulator
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| 310. | Life of Revenge | LPS Reaction | AyChristene Reacts | 265 | Let's Play |
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| 311. | She's Gone!!! | DOKI DOKI LITERATURE CLUB LIVESTREAM Part 3 | 265 | | Doki Doki Literature Club!
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| 312. | Try Not To Laugh Challenge | Yuri On Ice On Crack | Hot Guy Buns and @Tatsunero | | 264 | |
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| 313. | Hetalia Meme Compilation | KinoMusic Reaction | AyChristene Reacts | 264 | |
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| 314. | Nyan Neko Sugar Girls | Try Not To Cringe Challenge | 263 | | Neko
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| 315. | FNAF Animation | Episode 14 | Tony Crynight Reaction | AyChristene Reacts | 263 | Show | Five Nights at Freddy's 2
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| 316. | A Chubby Holiday | iHasCupquake | Gang Beasts Animation | AyChristene Reacts | 262 | | Gang Beasts
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| 317. | Ballora's Song | FNAF Sister Location Animation | Cypercat Reaction | AyChristene Reacts | 262 | | Five Nights at Freddy's: Sister Location
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| 318. | Try Not To Laugh | Try Not To Spit Challenge | AyChristene Reacts | 261 | |
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| 319. | 20k #OfficialBuddies | Milestone Video | Omegle, Special Giveaway, & More | AyChristene Celebrates | 260 | |
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| 320. | BACK TOGETHER FNAF by The Stupendium | AyChristene Reacts | 260 | | Five Nights at Freddy's VR: Help Wanted
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| 321. | Roblox Citizens | RoCitizens | Rebecca is Lazy | Online Gameplay | 258 | | Roblox
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| 322. | Roblox High School | Roblox With #OfficialBuddies | We Gettin' Turnt | AyChristene Games | 255 | | Roblox
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| 323. | These Ponies Go Hard | Epic Pie Time | Alligator Tub Productions Reaction | AyChristene Reacts | 254 | Let's Play |
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| 324. | SHE SAVAGE!! | 10 Things to Say to Your Enemies | LPSskittles Reaction | AyChristene Reacts | 252 | Let's Play |
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| 325. | Freeze Your Brain | Heathers Animatic | MissyAsylum Reaction | AyChristene Reacts | 252 | | Freeze!
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| 326. | Here's Freddy | FNAF Animation | Episode 10 | Tony Crynight Reaction | AyChristene Reacts | 251 | Show | Five Nights at Freddy's
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| 327. | I CALLED MY HUSBAND | SLENDER THE ARRIVAL NINTENDO SWITCH GAMEPLAY | 250 | | Slender: The Arrival
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| 328. | Murder Mystery 2 | Roblox | I Want To Murder | Online Gameplay | 249 | | Roblox
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| 329. | Fairy Tail On Crack | Try Not To Laugh | AyChristene Reacts | 249 | | Fairy Tail
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| 330. | MANGLE DANCE PARTY | FNAF 2 ROLEPLAY IN ROBLOX | 247 | | Five Nights at Freddy's 2
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| 331. | Yandere Simulator Adventures | Bijuu Mike Reaction | AyChristene Reacts | 244 | | Yandere Simulator
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| 332. | Meet Me Inside | Hamilton Animatic | Devon Pasternak Reaction | AyChristene Reacts | 243 | | Meet Me
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| 333. | LPS Springtrap House Tour | LPS bluesparkle Reaction | AyChristene Reacts | 243 | Let's Play |
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| 334. | Super Fail | Try not to Aww Challenge | AyChristene Reacts | 241 | |
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| 335. | KILLED SOMEONE TRYING BITLIFE FOR THE FIRST TIME | BITLIFE GAMEPLAY | 241 | | BitLife - Life Simulator
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| 336. | DISCOVERING FRAN BOW | Chapter 1 & Chapter 2 | 240 | | Fran Bow
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| 337. | WE NEED A NEW SHERIFF | ROBLOX MURDER MYSTERY 2 | 239 | | Roblox
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| 338. | BEST EVER | Jacksepticeye Animated | Super Mario Maker | James Farr Reaction | AyChristene Reacts | 238 | | Super Mario Maker
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| 339. | Baby Animals Are Ugly |Try Not To Aww Challenge | AyChristene Reacts | 238 | |
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| 340. | My Disney Channel Audition | Try Not To Sing Challenge | Disney Channel Songs | AyChristene Reacts | 237 | |
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| 341. | Sister Location | Part 5 | Beat Night 3 | PC Gameplay | 237 | | Five Nights at Freddy's: Sister Location
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| 342. | Gang Beasts Animated Short | iHasCupquake Animation | AyChristene Reacts | 237 | | Gang Beasts
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| 343. | Try Not To Laugh | I Almost Threw Up | AyChristene Reacts | 235 | |
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| 344. | Washington On Your Side | Hamilton Animatic | joey hazel Reaction | AyChristene Reacts | 234 | |
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| 345. | PPAP | Pen Pineapple Apple Pen | CHEE TEE Teoh Reaction | AyChristene Reacts | 234 | |
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| 346. | So... | ROBLOX MURDER MYSTERY W/ @JazzyGuns | COLLABS OF AyChristeneMas 2020 | 234 | | Roblox
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| 347. | T Is For Toilet | Beware The Toilet Will Kill You | Lee Hardcastle Reaction | AyChristene Reacts | 233 | |
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| 348. | Try Not To Cringe | %&#@ You @xHeyCharliex | AyChristene Reacts | 233 | |
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| 349. | Hello Neighbor | I Almost Passed Out! | PC Gameplay | 230 | | Hello Neighbor
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| 350. | Try No To Be Scared Challenge | Scaretober | AyCristene Reacts | 229 | |
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| 351. | Speedpaint | #BuddyArt | I Want This Outfit | #BuddyReacts | AyChristene Reacts | 229 | | The Outfit
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| 352. | Dora the Explorer Movie Trailer (with Ariel Winter) | Reaction Video | 229 | Preview |
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| 353. | Fight For Me | Heathers Animatic | bluetala Reaction | AyChristene Reacts | 229 | |
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| 354. | I WANT TO THANK YOU | OFFICIAL BUDDY DAY 2020 | 228 | |
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| 355. | BRAIN FULL OF IDEAS | ANIMATED AYCHRISTENE | 227 | |
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| 356. | My Old Videos | Reacting To Old Videos | AyChristene Reacts | 227 | |
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| 357. | RIP Headphones | Horror Elevator | Roblox | Online Gameplay | 227 | | Roblox
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| 358. | I DID NOT CURSE! - EVIEBOT [PC] GAMEPLAY #2 | 227 | |
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| 359. | SFM FNAF Pizza | Limay Sahara Reaction | AyChristene Reacts | 227 | |
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| 360. | I'm Senpai | Part 23 | Yandere Simulator Easter eggs & Glitches | 226 | | Yandere Simulator
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| 361. | OMG THAT COW!!! | LITTLE MISFORTUNE GAMEPLAY EP 4 | 224 | | Little Misfortune
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| 362. | Yandere Meme Compilation | Try not to laugh | Part 9 | AyChristene Reacts | 223 | |
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| 363. | AlliCatt Vines | Try Not To Laugh, Smile, or Grin Challenge | AyChristene Reacts | 222 | |
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| 364. | RWBY Black Trailer | Rooster Teeth Reaction | AyChristene Reacts | 222 | Preview |
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| 365. | Try Not To Laugh | Carl Poppa | La Jiggy Jar Jar Doo Reaction | AyChristene Reacts | 222 | |
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| 366. | THROW SOME GLITTER | LITTLE MISFORTUNE GAMEPLAY EP 3 | 222 | | Little Misfortune
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| 367. | How to Make Five Nights at Freddy's 4 Not Scary | I Can Be Brave | AyChristene Reacts | 222 | Guide | Five Nights at Freddy's 4
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| 368. | Surgeon Simulator Animation | iHasCupQuake Reaction | AyChristene Reacts | 220 | | Surgeon Simulator
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| 369. | Yandere Simulator Gameplay | Bars, Food, & Murder | Mission Mode | PC Gameplay | 220 | | Yandere Simulator
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| 370. | You Sing You Lose | X Happy Moments ENG | Try Not To Sing | AyChristene Reacts | 218 | |
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| 371. | Murder Mystery 2 | Roblox | Online Gameplay | 217 | | Roblox
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| 372. | Sailor Moon On Crack | Try Not To Laugh | AyChristene Reacts | 216 | | Sailor Moon
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| 373. | Schuyler Defeated | Hamilton Animatic | SaffeeBear & Allison Coon Reaction | AyChristene Reacts | 216 | | Allison
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| 374. | The Prologue | DANGANRONPA TRIGGER HAPPY HAVOC #1 | 216 | | Danganronpa: Trigger Happy Havoc
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| 375. | LPS How To Get A Boyfriend | MusicGirl Pro Reaction | AyChristene Reacts | 216 | Let's Play |
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| 376. | What Comes Next? | Hamilton Animatic | Captain Sealant Reaction | AyChristene Reacts | 214 | |
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| 377. | I PEED MYSELF | ROBLOX MURDER MYSTERY 2 GAMEPLAY | 214 | | Roblox
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| 378. | Addicted To Pizza | FNAF Reaction | AyChristene Reacts | 213 | | Five Nights at Freddy's
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| 379. | Porkchop n Flatscreen | Episode 18 | Emezie Okorafor | AyChristene Reacts | 213 | Show |
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| 380. | The Rendezvous Storyboard Animatic | Maksn Reaction | AyChristene Reacts | 213 | |
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| 381. | THE FLOOR IS LAVA 2 | ROBLOX | AYCHRISTENE Online Gameplay | 212 | | Roblox
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| 382. | Come See My Room | Room Tour | 40k Subs Milestone Video | AyChristene Vlogs | 212 | Vlog |
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| 383. | #NOLOYALTY | ROBLOX FLEE THE FACILITY GAMEPLAY | 212 | | Roblox
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| 384. | Undertale | PART 3 | I'm Killing These Dogs | PC Gameplay | 209 | | Undertale
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| 385. | Childhood Ruined | ADHD Reaction | AyChristene Reacts | 209 | |
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| 386. | After Ever After | DISNEY Parody | Paint Reaction | AyChristene Reacts | 208 | |
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| 387. | Yorktown | Hamilton Animatic | 1010lilfoot Reaction | AyChristene Reacts | 208 | |
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| 388. | Funniest Banned Commercials 2017 | YesFunnyYes Reaction | AyChristene Reacts | 208 | |
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| 389. | Thank You Video | 1 Million Views Celebration | AyChristene Dances | 207 | |
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| 390. | THOSE DARN WASPS AGAIN!!! | ANIMAL CROSSING NEW HORIZONS GAMEPLAY | 205 | | Animal Crossing: New Horizons
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| 391. | WHAT IS THIS GAME??!! | LITTLE MISFORTUNE GAMEPLAY EP 2 | 205 | | Little Misfortune
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| 392. | 5 AM At Freddy's | Piemation Reaction | AyChristene Reacts | 205 | | Five Nights at Freddy's
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| 393. | The Walking Dead | Season 1 Episode 1| Telltale Games | PS4 Gameplay | 204 | Show | The Walking Dead
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| 394. | Buns And Burgers | Try Not To Laugh Challenge | iHasCupquake Animation | 204 | |
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| 395. | Salad Fingers | Episode 1 & 2 Reaction | AyChristene Reacts | 204 | Show |
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| 396. | A Little Misfortune Song by Random Encounters ft The Stupendium | Aychristene Reacts | 203 | | Little Misfortune
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| 397. | Markiplier Mustache | Part 24 | Yandere Simulator Easter eggs & Glitches | 203 | | Yandere Simulator
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| 398. | MUHAHAHAHAH! | ROBLOX MURDER MYSTERY 2 GAMEPLAY | 203 | | Roblox
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| 399. | The Sims 4 Pokemon | LaurenzSide Animation | VTAnimation Reaction | AyChristene Reacts | 203 | | The Sims 4
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| 400. | Hello, Neighbor! | I Hate This Guy | PC Gameplay | 201 | | Hello Neighbor
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