| 2021-12-01 | Specific Heat Capacity | Modeling Energy | High School Physics | Khan Academy | 7:32 | 12,818 | |
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| 2021-11-29 | Titrations of polyprotic acids | Acids and bases | AP Chemistry | Khan Academy | 8:44 | 34,122 | |
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| 2021-11-27 | All in for Education: Keep Khan Academy Free | 2:21 | 163,938 | |
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| 2021-11-11 | Khan Academy Ed Talks with Pedro De Bruyckere - Thursday, November 11 | 31:49 | 13,558 | |
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| 2021-11-09 | Khan Academy Ed Talks with Kara Bobroff - Tuesday, November 9 | 34:04 | 10,438 | |
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| 2021-11-03 | Part to whole ratio word problem using tables | 2:36 | 15,422 | |
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| 2021-09-21 | Announcing Khan Academy India talent search 2021 | 0:24 | 61,293 | |
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| 2021-09-18 | National SAT Practice Test Day 2021 | 3:22:36 | 82,218 | |
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| 2021-09-18 | Acid–base indicators | Acids and bases | AP Chemistry | Khan Academy | 7:05 | 40,000 | |
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| 2021-09-18 | Weak base–strong acid titrations | Acids and bases | AP Chemistry | Khan Academy | 10:34 | 22,035 | |
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| 2021-09-18 | Weak acid–strong base titrations | Acids and bases | AP Chemistry | Khan Academy | 12:09 | 24,838 | |
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| 2021-09-18 | Strong acid–strong base titrations | Acids and bases | AP Chemistry | Khan Academy | 9:00 | 7,834 | |
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| 2021-09-15 | Homeroom with Sal and Wendy Kopp - Wednesday, September 15 | 37:11 | 8,611 | |
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| 2021-09-14 | Opportunities for high school and college tutors | 2:48 | 38,398 | |
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| 2021-09-04 | Second "Ask Sal anything" session focused on life advice | 29:34 | 29,357 | |
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| 2021-09-03 | Buffer capacity | Acids and bases | AP Chemistry | Khan Academy | 10:18 | 21,844 | |
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| 2021-09-02 | Khan Academy Ed Talks with Fenesha Hubbard - Thursday, September 2 | 30:01 | 8,675 | |
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| 2021-08-27 | Sal answers questions from attendees at his Schoolhouse.world series | 47:39 | 24,101 | |
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| 2021-08-24 | Buffer range | Acids and bases | AP Chemistry | Khan Academy | 5:17 | 15,629 | |
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| 2021-08-24 | Methods for preparing buffers | Acids and bases | AP Chemistry | Khan Academy | 10:26 | 16,833 | |
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| 2021-08-24 | Henderson–Hasselbalch equation | Acids and bases | AP Chemistry | Khan Academy | 7:34 | 108,310 | |
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| 2021-08-24 | Properties of buffers | Acids and bases | AP Chemistry | Khan Academy | 6:59 | 9,287 | |
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| 2021-08-24 | Cellular respiration | Matter and energy in organisms | High school biology | Khan Academy | 7:40 | 10,863 | Vlog |
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| 2021-08-19 | Khan Academy Ed Talks with Sophie Bosmeny - Thursday, August 19 | 30:37 | 10,782 | |
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| 2021-08-18 | Khan Academy Ed Talks with Adam Green, PhD - Wednesday, August 18 | 32:32 | 8,345 | |
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| 2021-08-17 | Cell division and organism growth | High school biology | Khan Academy | 6:37 | 14,293 | Vlog |
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| 2021-08-17 | Homeroom with Sal & Vas Narasimhan - Tuesday, August 17 | 31:15 | 9,419 | |
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| 2021-08-17 | Natural selection and evolution | High school biology | Khan Academy | 6:30 | 10,874 | Vlog |
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| 2021-08-17 | Genes, traits, and the environment | Inheritance and variation | High school biology | Khan Academy | 3:33 | 7,212 | Vlog |
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| 2021-08-17 | Gene expression and regulation | Inheritance and variation | High school biology | Khan Academy | 7:12 | 20,227 | Vlog |
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| 2021-08-16 | Stratospheric Ozone Depletion| Global change| AP Environmental Science| Khan Academy | 5:09 | 11,075 | |
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| 2021-08-16 | Pathogens and the environment| AP Environmental science| Khan Academy | 4:37 | 3,504 | |
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| 2021-08-16 | Nonrenewable Energy Resources| AP Environmental science| Khan Academy | 7:35 | 13,350 | |
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| 2021-08-16 | Integrated pest management| Land and Water Use| AP Environmental science| Khan Academy | 6:43 | 3,700 | |
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| 2021-08-16 | Demographic transition model| Human populations| AP Environmental science| Khan Academy | 7:19 | 7,328 | |
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| 2021-08-11 | Weak acid–weak base reactions | Acids and bases | AP Chemistry | Khan Academy | 7:11 | 25,623 | |
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| 2021-08-11 | Weak base–strong acid reactions | Acids and bases | AP Chemistry | Khan Academy | 6:28 | 15,664 | |
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| 2021-08-11 | Worked example: Calculating the pH after a weak acid–strong base reaction (excess acid) | 9:04 | 31,903 | |
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| 2021-08-11 | Weak acid–strong base reactions | Acids and bases | AP Chemistry | Khan Academy | 8:02 | 17,031 | |
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| 2021-08-11 | Strong acid–strong base reactions | Acids and bases | AP Chemistry | Khan Academy | 9:29 | 12,686 | |
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| 2021-08-10 | Sal's back to school 2021 message | 2:29 | 158,905 | |
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| 2021-08-06 | LearnStorm 2021 - Khan Academy LearnStorm | 2:25 | 127,195 | |
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| 2021-08-05 | Adaptation and environmental change | High school biology | Khan Academy | 9:18 | 9,756 | Vlog |
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| 2021-07-31 | Factors affecting acid strength | Acids and bases | AP Chemistry | Khan Academy | 8:39 | 25,237 | |
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| 2021-07-31 | Acid–base properties of salts | Acids and bases | AP Chemistry | Khan Academy | 13:33 | 30,106 | |
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| 2021-07-31 | Weak base equilibria | Acids and bases | AP Chemistry | Khan Academy | 9:30 | 5,732 | |
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| 2021-07-31 | Worked example: Finding the percent ionization of a weak acid | AP Chemistry | Khan Academy | 6:50 | 42,649 | |
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| 2021-07-31 | Weak acid equilibria | Acids and bases | AP Chemistry | Khan Academy | 11:10 | 8,790 | |
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| 2021-07-31 | Strong base solutions | Acids and bases | AP Chemistry | Khan Academy | 5:27 | 2,846 | |
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| 2021-07-31 | Strong acid solutions | Acids and bases | AP Chemistry | Khan Academy | 6:18 | 3,730 | |
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| 2021-07-31 | Worked examples: Calculating [H₃O⁺] and pH | Acids and bases | AP Chemistry | Khan Academy | 7:05 | 4,656 | |
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| 2021-07-31 | The pH scale | Acids and bases | AP Chemistry | Khan Academy | 8:49 | 11,788 | |
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| 2021-07-31 | Autoionization of water | Acids and bases | AP Chemistry | Khan Academy | 9:01 | 10,863 | |
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| 2021-07-29 | Digital and analog information | Information Technologies | High School Physics | Khan Academy | 4:11 | 8,886 | Vlog |
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| 2021-07-29 | Wave properties | Wave properties | High School Physics | Khan Academy | 6:48 | 10,975 | |
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| 2021-07-29 | Calculating height using energy | Modeling Energy | High School Physics | Khan Academy | 6:29 | 9,141 | |
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| 2021-07-29 | Calculating velocity using energy | Modeling Energy | High School Physics | Khan Academy | 8:35 | 3,574 | |
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| 2021-07-29 | Natural selection and adaptation | High school biology | Khan Academy | 8:52 | 16,426 | Vlog |
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| 2021-07-28 | Acid Rain| Atmospheric Pollution| AP Environmental science| Khan Academy | 7:41 | 13,144 | |
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| 2021-07-27 | Evolution of group behavior | Evolution and natural selection | High school biology | Khan Academy | 4:14 | 9,235 | Vlog |
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| 2021-07-26 | Ocean acidification| Global Change| AP Environmental science| Khan Academy | 5:25 | 7,067 | |
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| 2021-07-26 | Science, technology, and the environment | High school biology | Khan Academy | 6:25 | 5,271 | Vlog |
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| 2021-07-23 | Solid waste disposal| Aquatic and Terrestrial Pollution| AP Environmental science| Khan Academy | 7:56 | 12,974 | |
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| 2021-07-22 | Extinction | Adaptation and environmental change | High school biology | Khan Academy | 5:33 | 12,282 | Vlog |
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| 2021-07-21 | Species and the environment | High school biology | Khan Academy | 4:23 | 6,463 | Vlog |
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| 2021-07-21 | Introduction to sustainability| Land and water use| AP Environmental science| Khan Academy | 6:21 | 11,993 | |
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| 2021-07-19 | Heat transfer | Thermodynamics | High school physics | Khan Academy | 6:04 | 13,440 | |
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| 2021-07-19 | Solar Energy| Energy Resources and Consumption| AP Environmental science| Khan Academy | 6:48 | 5,850 | |
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| 2021-07-19 | The Indefinite Article | Parts of Speech | Grammar | Khan Academy | 4:43 | 10,202 | |
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| 2021-07-16 | Pollution and human health| Aquatic and Terrestrial Pollution| Khan Academy | 6:26 | 8,599 | |
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| 2021-07-15 | Mendelian inheritance and Punnett squares | High school biology | Khan Academy | 7:24 | 26,127 | Vlog |
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| 2021-07-15 | Sources of genetic variation | Inheritance and variation | High school biology | Khan Academy | 7:55 | 30,043 | Vlog |
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| 2021-07-14 | Homeroom with Sal & David Siegel - Wednesday, July 14 | 31:29 | 5,226 | |
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| 2021-07-14 | Feedback in living systems | Growth and feedback in organisms | High school biology | Khan Academy | 8:15 | 3,725 | Vlog |
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| 2021-07-14 | Inertial Mass vs. Gravitational Mass | Circular motion and gravitation | AP Physics 1 | Khan Academy | 8:12 | 16,057 | |
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| 2021-07-14 | Work-Energy Principle Example | Energy and Momentum | AP Physics 1 | Khan Academy | 7:45 | 5,030 | |
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| 2021-07-14 | Changes in Momentum Worked Examples | Momentum and Impulse | AP Physics 1 | Khan Academy | 9:00 | 8,050 | |
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| 2021-07-14 | Torque Basics | Simple harmonic motion and rotational motion | AP Physics 1 | Khan Academy | 9:40 | 6,768 | |
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| 2021-07-14 | Period of a Pendulum | Simple harmonic motion and rotational motion | AP Physics 1 | Khan Academy | 9:25 | 9,978 | |
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| 2021-07-13 | Dihybrid cross and the Law of Independent Assortment | High school biology | Khan Academy | 9:08 | 85,934 | Vlog |
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| 2021-07-12 | Energy at the microscopic scale | Introduction to energy | High school physics | Khan Academy | 5:58 | 5,696 | |
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| 2021-07-12 | Energy and fields | Introduction to energy | High school physics | Khan Academy | 4:46 | 3,065 | |
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| 2021-07-12 | What is energy? | Introduction to energy | High school physics | Khan Academy | 3:39 | 36,401 | |
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| 2021-07-12 | Calculating gravitational potential energy | Modeling energy | High school physics | Khan Academy | 4:33 | 52,803 | |
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| 2021-07-12 | Calculating kinetic energy | Modeling energy | High school physics | Khan Academy | 5:28 | 10,792 | |
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| 2021-07-12 | Energy in fields | Introduction to energy | High school physics | Khan Academy | 4:31 | 4,476 | |
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| 2021-07-12 | Electromagnetic radiation emission | Electromagnetic Radiation | High School Physics | Khan Academy | 5:21 | 7,613 | |
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| 2021-07-08 | pH and solubility | Equilibrium | AP Chemistry | Khan Academy | 5:14 | 14,392 | |
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| 2021-07-08 | The common-ion effect | Equilibrium | AP Chemistry | Khan Academy | 10:08 | 37,611 | |
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| 2021-07-08 | Worked example: Predicting whether a precipitate forms by comparing Q and Kₛₚ | Khan Academy | 8:16 | 9,819 | |
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| 2021-07-08 | Worked example: Calculating solubility from Kₛₚ | Equilibrium | AP Chemistry | Khan Academy | 4:52 | 9,580 | |
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| 2021-07-08 | Introduction to solubility equilibria | Equilibrium | AP Chemistry | Khan Academy | 8:17 | 39,385 | |
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| 2021-07-08 | Worked example: Using Le Chȃtelier’s principle to predict shifts in equilibrium | Khan Academy | 3:58 | 3,894 | |
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| 2021-07-08 | Worked example: Calculating the equilibrium total pressure after a change in volume | Khan Academy | 7:11 | 7,240 | |
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| 2021-07-08 | Le Chȃtelier’s principle: Changing temperature | Equilibrium | AP Chemistry | Khan Academy | 11:16 | 17,699 | |
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| 2021-07-08 | Le Chȃtelier’s principle: Changing volume | Equilibrium | AP Chemistry | Khan Academy | 11:09 | 8,594 | |
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| 2021-07-08 | Le Chȃtelier’s principle: Changing concentration | Equilibrium | AP Chemistry | Khan Academy | 8:38 | 6,849 | |
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| 2021-07-08 | Worked example: Using the reaction quotient to find equilibrium partial pressures | Khan Academy | 6:31 | 17,642 | |
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| 2021-07-08 | Using the reaction quotient | Equilibrium | AP Chemistry | Khan Academy | 7:50 | 6,488 | |
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| 2021-07-08 | Worked example: Calculating equilibrium concentrations from initial concentrations | Khan Academy | 5:29 | 83,404 | |
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