| Densha de Go! (1997) | 2,883,134 | 1,394 |
| Densha de Go! EX (1998) | 609,910 | 22 |
| Densha de GO! Final (2004) | 768,114 | 231 |
| Densha de Go! Nagoya Railroad (2000) | 7,038 | 21 |
| Densha de GO! Professional (1999) | 5,957 | 10 |
| Densha de Go! Professional 2 (2003) | 535,014 | 133 |
| Dental Strike (2024) | 6 | 2 |
| Dentures and Demons 2 (2020) | 1,251,212 | 537 |
| Depanneur Nocturne (2020) | 18,147 | 55 |
| Department 14 (2023) | 2,541 | 15 |
| Depersonalization (2022) | 68,622 | 209 |
| Depixtion (2019) | 2,262 | 18 |
| DEPO : Death Epileptic Pixel Origins (2022) | 3,760 | 43 |
| Deponia (2012) | 74,064,477 | 17,326 |
| Deponia Doomsday (2016) | 20,314,457 | 6,276 |
| Deponia: The Complete Journey (2014) | 1,139,252 | 6,345 |
| DepowerBall (2023) | 2,528 | 21 |
| Depraved (2018) | 3,256,154 | 1,558 |
| Depression Quest (2013) | 865,804 | 155 |
| Depression The Game (2018) | 123,747 | 31 |
| Depth (2014) | 191,926,702 | 7,713 |
| Depth Dwellers (1994) | 436,001 | 100 |
| Depth Hunter (2012) | 984,928 | 171 |
| Depth Hunter 2: Deep Dive (2014) | 703,813 | 190 |
| Depth of Extinction (2018) | 193,540 | 264 |
| Depthcharge (1977) | 10,551 | 40 |
| Depthris (2023) | 0 | 0 |
| Depths of Dread (2016) | 440 | 2 |
| Depths of Faveg (2024) | 240 | 2 |
| Depths of Helheim (2023) | 13,454 | 4 |
| Depths of Insanity (2023) | 18,298 | 19 |
| Depths of Limbo (2017) | 10,200 | 23 |
| Depths of Madness (2019) | 632,809 | 57 |
| Depths of Peril (2007) | 253,175 | 83 |
| Deputinization (2023) | 1,027 | 5 |
| Der Anzeigenhauptmeister (2024) | 1,261,225 | 43 |
| Der Blaue Diamant (2020) | 0 | 0 |
| Der flinke Architekt (1983) | 947 | 3 |
| Der Fluch der Osterinsel (2010) | 10,938 | 6 |
| Der Geisterjäger / The Ghost Hunter (2021) | 1,094 | 8 |
| Der Geistermeister (2023) | 52 | 2 |
| Der Geisterturm / The Ghost Tower (2020) | 522 | 3 |
| Der Klomanager (2000) | 15,741 | 16 |
| Der Königsruf (2024) | 37 | 1 |
| Der Pfad des Pinguins (2024) | 43 | 3 |
| Der Planer (1994) | 513,871 | 465 |
| Der Schatz der Delfine (2009) | 48 | 2 |
| Déraciné (2018) | 2,385,536 | 630 |
| Derail Valley (2019) | 27,649,063 | 9,599 |
| Derby Jockey 2 (1995) | 11,302 | 8 |
| Derby Jockey: Kishou e no Michi (1994) | 4,849 | 10 |
| Derby Owners Club (2012) | 90,051 | 65 |
| Derby Owners Club 2000 (2000) | 152 | 1 |
| Derby Stallion (1991) | 11,464 | 19 |
| Derby Stallion (1993) | 760 | 3 |
| Derby Stallion (1997) | 4,220,205 | 877 |
| Derby Stallion '04 (2004) | 13,941 | 22 |
| Derby Stallion '96 (1996) | 52,658 | 25 |
| Derby Stallion '99 (1999) | 5,672 | 26 |
| Derby Stallion 64 (2001) | 108,572 | 108 |
| Derby Stallion Advance (2002) | 55,149 | 21 |
| Derby Stallion DS (2008) | 6,549 | 10 |
| Derby Stallion GOLD (2014) | 209,393 | 110 |
| Derby Stallion II (1994) | 78,968 | 32 |
| Derby Stallion III (1995) | 1,386,444 | 170 |
| Derby Stallion Masters (2016) | 2,608,815 | 489 |
| Derby Stallion P (2006) | 21,944 | 16 |
| Derby Stallion: Best Race (1991) | 13,621 | 23 |
| Derby Time 2006 (2006) | 5,480 | 60 |
| DERE EXE: Rebirth of Horror (2018) | 9,605,468 | 591 |
| Derek Jeter Pro Baseball 2008 (2008) | 16,355 | 7 |
| Derek Jeter Real Baseball (2009) | 22,756 | 4 |
| Derelict Fleet (2017) | 0 | 0 |
| Derelict Void (2021) | 73,689 | 90 |
| Dereliction: 2022 (2024) | 570 | 7 |
