| DuckTales 2 (1993) | 8,573,366 | 3,430 |
| DuckTales: Remastered (2013) | 241,055,716 | 12,244 |
| DuckTales: Scrooge's Loot (2013) | 284,052 | 34 |
| DuckTales: The Quest for Gold (1990) | 517,821 | 108 |
| Duckthing's Rolling Rooms (2024) | 124 | 3 |
| Ducky Runnerz (2024) | 1,819 | 8 |
| Ducky's Delivery Service (2023) | 4,378 | 35 |
| Duct Tape Simulator (2023) | 0 | 0 |
| Dude, Stop (2018) | 124,155,869 | 1,415 |
| Dude, Where Is My Beer? (2020) | 0 | 0 |
| Dudes with Attitude (1990) | 0 | 0 |
| Dudley and the Mysterious Tower (2020) | 12,822 | 22 |
| Due Process (2020) | 13,325,972 | 707 |
| Duel Corp. (2023) | 0 | 0 |
| Duel Girl (2019) | 0 | 0 |
| Duel Love (2008) | 0 | 0 |
| Duel Masters Kaijudo Showdown (2004) | 36,887 | 255 |
| Duel Masters Nettou! Battle Arena (2004) | 191,790 | 139 |
| Duel Masters Shadow of the Code (2005) | 0 | 0 |
| Duel Masters: Sempai Legends (2004) | 92,612 | 129 |
| Duel on Board (2021) | 83,342 | 35 |
| The Duel: Test Drive II (1989) | 7,031,642 | 913 |
| Duel: The Art of Combat (2009) | 8 | 1 |
| DUELANT (2025) | 0 | 0 |
| DUELEUM (2017) | 0 | 0 |
| Dueling Network (2006) | 31,470,390 | 4,598 |
| Duelists of Eden (2024) | 248,280 | 230 |
| Duelite (2024) | 0 | 0 |
| Duels of Fortune (2023) | 23,739 | 33 |
| DuelVox: Max Quality (2021) | 0 | 0 |
| Duelyst (2016) | 6,376,270 | 6,965 |
| Duet (2013) | 768,676 | 315 |
| Duke Dashington Remastered (2017) | 61,425 | 99 |
| Duke Grabowski: Mighty Swashbuckler! (2016) | 47,167 | 80 |
| Duke Nukem (1991) | 12,838,321 | 5,371 |
| Duke Nukem 3D (1996) | 102,816,440 | 31,528 |
| Duke Nukem 64 (1997) | 2,324,938 | 1,286 |
| Duke Nukem Advance (2002) | 0 | 0 |
| Duke Nukem Forever (2011) | 157,014,804 | 18,738 |
| Duke Nukem II (1993) | 2,813,873 | 1,211 |
| Duke Nukem Manhattan Project (2010) | 207,698 | 167 |
| Duke Nukem Mobile (2004) | 16,317 | 49 |
| Duke Nukem: Critical Mass (2011) | 366,297 | 146 |
| Duke Nukem: Land of the Babes (2000) | 1,635,302 | 651 |
| Duke Nukem: Manhattan Project (2002) | 2,188,672 | 1,586 |
| Duke Nukem: Time to Kill (1998) | 3,143,423 | 1,565 |
| Duke Nukem: Total Meltdown (1997) | 933,311 | 462 |
| Duke Nukem: Zero Hour (1999) | 1,990,426 | 794 |
| Duke of Defense (2019) | 0 | 0 |
| Duke: Nuclear Winter (1997) | 39,627 | 211 |
| The Dukes of Hazzard (1984) | 15,828,195 | 1,825 |
| The Dukes of Hazzard II: Daisy Dukes It Out (2000) | 79,996 | 48 |
| The Dukes of Hazzard: Racing for Home (1999) | 274,506 | 143 |
| The Dukes of Hazzard: Return of the General Lee (2004) | 0 | 0 |
| Duline (2022) | 23 | 1 |
| Dull Grey (2021) | 96,421 | 142 |
| Dumb Little Creatures (2019) | 0 | 0 |
| Dumb Ways to Die 2: The Games (2014) | 348,448,652 | 1,701 |
| Dumball Rush (2024) | 25 | 3 |
| DumbBots: Hello World (2020) | 0 | 0 |
| Dumbino (2025) | 1,886 | 5 |
| Dummy Dungeon (2024) | 7 | 3 |
| Dummy Pirates: Ocean Tales (2023) | 22 | 3 |
| Dun Darach (1985) | 0 | 0 |
| Dunamis 15 (2011) | 0 | 0 |
| Dune (1992) | 128,325,029 | 4,997 |
| Dune 2000 (1998) | 8,300,827 | 11,656 |
| Dune Dasher (2023) | 0 | 0 |
| Dune II (1992) | 15,626,703 | 9,568 |
| Dune: Awakening (2025) | 132,540,456 | 20,253 |
| Dune: Imperium (2023) | 5,170,844 | 1,236 |
| Dune: Spice Wars (2022) | 21,097,233 | 5,737 |
| Dunes of Valor (2024) | 0 | 0 |
| Dung Beetle Strike (2020) | 947 | 5 |
| Dung Beetles (1982) | 841,841 | 69 |
