| Disc Room (2020) | 6,822,564 | 1,166 |
| Disc Space (2020) | 541,457 | 48 |
| Disciples II: Dark Prophecy (2002) | 26,191,169 | 20,344 |
| Disciples III: Renaissance (2009) | 7,576,531 | 3,527 |
| Disciples of Steel (1993) | 7,432 | 16 |
| Disciples of Varahces (2023) | 0 | 0 |
| Disciples: Liberation (2021) | 7,092,221 | 6,783 |
| Disciples: Sacred Lands (1999) | 9,803,622 | 3,658 |
| Discmaster (2020) | 591 | 2 |
| Disco Dodgeball Remix (2018) | 41,261 | 56 |
| Disco Elysium (2019) | 88,745,339 | 47,170 |
| Disco No. 1 (1982) | 10,019 | 24 |
| Disco Samurai (2025) | 2,910 | 31 |
| Disco Simulator (2024) | 849,569 | 484 |
| Disco Time 80s VR (2017) | 6,618 | 9 |
| Disco Zoo (2014) | 551,161 | 77 |
| Discolored (2019) | 528,629 | 383 |
| Discolored 2 (2025) | 9,408 | 81 |
| Discontinue (2019) | 28,499 | 37 |
| Discord Times (2004) | 1,009,426 | 676 |
| Discounty (2025) | 1,744,330 | 912 |
| Discouraged Workers (2015) | 6,648 | 18 |
| Discouraged Workers TEEN (2016) | 614 | 9 |
| Discovery (2012) | 172,055,166 | 1,230 |
| Discovery Kids: Dolphin Discovery (2008) | 328 | 6 |
| Discovery Kids: Parrot Pals (2009) | 4,673 | 13 |
| Discovery Kids: Pony Paradise (2009) | 354 | 5 |
| Discovery Kids: Puppy Playtime (2009) | 7,921 | 8 |
| Discovery Kids: Snake Safari (2009) | 2,614 | 8 |
| Discovery Kids: Spider Quest (2009) | 4,641 | 5 |
| Discovery! A Seek and Find Adventure (2008) | 8,159 | 12 |
| Discrepant (2019) | 12,062 | 25 |
| The Discrete Era (2024) | 0 | 0 |
| Discs of Tron (1983) | 247,131 | 117 |
| DiscStorm (2015) | 19,107 | 39 |
| Discvivors (2022) | 7 | 1 |
| Discworld (1995) | 3,784,193 | 2,870 |
| Discworld MUD (1992) | 67,958 | 17 |
| Discworld Noir (1999) | 1,304,597 | 1,024 |
| Disdoored (2018) | 33,657 | 16 |
| Disease: -Hidden Object- (2018) | 25,907 | 61 |
| Disgaea 2: Cursed Memories (2006) | 9,164,234 | 5,126 |
| Disgaea 3: Absence of Justice (2008) | 7,236,426 | 1,904 |
| Disgaea 4: A Promise Unforgotten (2011) | 13,790,048 | 6,588 |
| Disgaea 5: Alliance of Vengeance (2015) | 20,741,531 | 19,040 |
| Disgaea 6: Defiance of Destiny (2021) | 7,001,884 | 5,798 |
| Disgaea 7: Vows of the Virtueless (2023) | 4,463,686 | 4,552 |
| Disgaea D2: A Brighter Darkness (2013) | 6,076,397 | 2,568 |
| Disgaea Infinite (2009) | 876,508 | 201 |
| Disgaea RPG (2019) | 4,369,813 | 5,244 |
| Disgaea: Hour of Darkness (2003) | 18,668,676 | 15,475 |
| Disgraced (2016) | 846,052 | 78 |
| Disharmonia (2022) | 24,056 | 22 |
| Dishaster (1983) | 7,733 | 14 |
| Dishonored (2012) | 572,972,388 | 140,303 |
| Dishonored 2 (2016) | 300,971,299 | 82,913 |
| Dishonored: Death of the Outsider (2017) | 26,240,987 | 14,686 |
| The Dishwasher: Dead Samurai (2009) | 404,187 | 269 |
| The Dishwasher: Vampire Smile (2011) | 4,957,887 | 1,318 |
| Dishwashing Simulator (2024) | 2,960,876 | 334 |
| Disintegration (2020) | 19,765,483 | 2,608 |
| Disjunction (2021) | 618,383 | 463 |
| Disk Dashers (2023) | 0 | 0 |
| Dislyte (2022) | 40,721,645 | 11,930 |
| The Disney Afternoon Collection (2017) | 2,915,750 | 1,948 |
| Disney Art Academy (2016) | 2,059,317 | 208 |
| Disney Channel All Star Party (2010) | 661,004 | 101 |
| Disney Classic Games Aladdin and The Lion King (2019) | 37,920 | 146 |
| Disney Classic Games: Aladdin and The Lion King (2019) | 2,951,100 | 899 |
| Disney Dream Treats (2015) | 45,724 | 36 |
| Disney Dreamlight Valley (2022) | 117,058,542 | 123,579 |
| Disney Emoji Blitz (2016) | 4,095,538 | 1,413 |
| Disney Epic Mickey: Rebrushed (2024) | 10,092,429 | 3,617 |
| Disney Fairies: Tinker Bell (2008) | 3,284,280 | 143 |
| Disney Fairies: Tinker Bell and the Great Fairy Rescue (2010) | 57,751 | 10 |
