| Disciples of Varahces (2023) | 0 | 0 |
| Disciples: Liberation (2021) | 7,090,534 | 6,752 |
| Disciples: Sacred Lands (1999) | 9,759,157 | 3,563 |
| Discmaster (2020) | 591 | 2 |
| Disco Dodgeball Remix (2018) | 41,261 | 56 |
| Disco Elysium (2019) | 87,231,402 | 46,819 |
| Disco No. 1 (1982) | 10,019 | 24 |
| Disco Samurai (2025) | 2,910 | 31 |
| Disco Simulator (2024) | 849,207 | 482 |
| Disco Time 80s VR (2017) | 6,618 | 9 |
| Disco Zoo (2014) | 551,161 | 77 |
| Discolored (2019) | 528,628 | 383 |
| Discolored 2 (2025) | 9,368 | 81 |
| Discontinue (2019) | 28,499 | 37 |
| Discord Times (2004) | 1,009,259 | 675 |
| Discounty (2025) | 1,355,636 | 827 |
| Discouraged Workers (2015) | 6,648 | 18 |
| Discouraged Workers TEEN (2016) | 614 | 9 |
| Discovery (2012) | 171,820,247 | 1,212 |
| Discovery Kids: Dolphin Discovery (2008) | 328 | 6 |
| Discovery Kids: Parrot Pals (2009) | 4,673 | 13 |
| Discovery Kids: Pony Paradise (2009) | 354 | 5 |
| Discovery Kids: Puppy Playtime (2009) | 7,921 | 8 |
| Discovery Kids: Snake Safari (2009) | 2,614 | 8 |
| Discovery Kids: Spider Quest (2009) | 4,641 | 5 |
| Discovery! A Seek and Find Adventure (2008) | 8,159 | 12 |
| Discrepant (2019) | 12,062 | 25 |
| The Discrete Era (2024) | 0 | 0 |
| Discs of Tron (1983) | 247,129 | 117 |
| DiscStorm (2015) | 19,107 | 39 |
| Discvivors (2022) | 7 | 1 |
| Discworld (1995) | 3,779,248 | 2,854 |
| Discworld MUD (1992) | 67,958 | 17 |
| Discworld Noir (1999) | 1,304,288 | 1,022 |
| Disdoored (2018) | 33,657 | 16 |
| Disease: -Hidden Object- (2018) | 25,907 | 61 |
| Disgaea 2: Cursed Memories (2006) | 9,158,964 | 5,106 |
| Disgaea 3: Absence of Justice (2008) | 7,233,595 | 1,900 |
| Disgaea 4: A Promise Unforgotten (2011) | 13,781,861 | 6,574 |
| Disgaea 5: Alliance of Vengeance (2015) | 20,731,849 | 18,974 |
| Disgaea 6: Defiance of Destiny (2021) | 6,998,547 | 5,784 |
| Disgaea 7: Vows of the Virtueless (2023) | 4,447,103 | 4,490 |
| Disgaea D2: A Brighter Darkness (2013) | 6,074,602 | 2,561 |
| Disgaea Infinite (2009) | 876,504 | 201 |
| Disgaea RPG (2019) | 4,369,120 | 5,239 |
| Disgaea: Hour of Darkness (2003) | 18,631,185 | 15,365 |
| Disgraced (2016) | 846,052 | 78 |
| Disharmonia (2022) | 24,056 | 22 |
| Dishaster (1983) | 7,733 | 14 |
| Dishonored (2012) | 572,350,570 | 139,976 |
| Dishonored 2 (2016) | 300,832,463 | 82,817 |
| Dishonored: Death of the Outsider (2017) | 26,215,937 | 14,619 |
| The Dishwasher: Dead Samurai (2009) | 404,050 | 269 |
| The Dishwasher: Vampire Smile (2011) | 4,957,376 | 1,311 |
| Dishwashing Simulator (2024) | 2,960,846 | 333 |
| Disintegration (2020) | 19,765,168 | 2,608 |
| Disjunction (2021) | 618,360 | 463 |
| Disk Dashers (2023) | 0 | 0 |
| Dislyte (2022) | 40,715,824 | 11,931 |
| The Disney Afternoon Collection (2017) | 2,854,527 | 1,872 |
| Disney Art Academy (2016) | 2,059,276 | 207 |
| Disney Channel All Star Party (2010) | 660,626 | 99 |
| Disney Classic Games Aladdin and The Lion King (2019) | 37,808 | 145 |
| Disney Classic Games: Aladdin and The Lion King (2019) | 2,949,889 | 896 |
| Disney Dream Treats (2015) | 45,724 | 36 |
| Disney Dreamlight Valley (2022) | 115,797,451 | 121,224 |
| Disney Emoji Blitz (2016) | 4,095,464 | 1,413 |
| Disney Epic Mickey: Rebrushed (2024) | 10,062,400 | 3,118 |
| Disney Fairies: Tinker Bell (2008) | 3,284,277 | 141 |
| Disney Fairies: Tinker Bell and the Great Fairy Rescue (2010) | 57,751 | 10 |
| Disney Friends (2007) | 203,451 | 88 |
| Disney Getaway Blast (2019) | 562,731 | 1,586 |
| Disney Golf (2002) | 1,667,672 | 232 |
| Disney Heroes: Battle Mode (2018) | 79,993,385 | 7,914 |
| Disney Illusion Island (2023) | 8,496,304 | 3,440 |
