| Special Forces (1992) | 180,569,879 | 6,916 |
| Special Gulag Rescue Operation (2022) | 40 | 3 |
| Special Jinsei Game (2003) | 8,942 | 4 |
| Special Operation 85: Hostage Rescue (2007) | 1,815 | 10 |
| Special Operations (1984) | 11,358,224 | 779 |
| Special Tee Shot (1996) | 0 | 0 |
| The Specialists (2002) | 25,454,695 | 2,814 |
| Species: Artificial Life, Real Evolution (2018) | 42,756,993 | 296 |
| Specimen Zero - Online horror (2021) | 51,105,100 | 5,513 |
| Specnaz: Project Wolf (2006) | 10,159 | 22 |
| Spectacular Sparky (2021) | 368,431 | 159 |
| Spectar (1980) | 11,094 | 35 |
| Spectator (2023) | 42,853,444 | 1,442 |
| Spectipede (1983) | 3,050 | 9 |
| Spectra (2015) | 2,930,337 | 447 |
| Spectraball (2008) | 43,795 | 192 |
| Spectral Force 3 (2006) | 202,524 | 224 |
| Spectral Force Chronicle (2005) | 24,306 | 5 |
| Spectral Force Genesis (2008) | 440 | 1 |
| Spectral Force Radical Elements (2004) | 4,680 | 3 |
| Spectral Gene (2007) | 143,739 | 43 |
| Spectral Scream (2024) | 0 | 0 |
| Spectral Souls: Resurrection of the Ethereal Empires (2005) | 298,907 | 183 |
| Spectral vs. Generation (2005) | 767,476 | 510 |
| Spectre (1982) | 81,540,103 | 4 |
| Spectre (1991) | 4,600,648 | 292 |
| The Spectre Files: Deathstalker (2020) | 430,767 | 48 |
| Spectrewoods (2019) | 405,026 | 502 |
| Spectrobes (2007) | 3,440,469 | 988 |
| Spectrobes: Beyond the Portals (2008) | 464,462 | 346 |
| Spectrobes: Origins (2009) | 4,647,194 | 1,275 |
| Spectrolite (2021) | 10,242 | 87 |
| Spectromancer (2009) | 135,848 | 154 |
| Spectron (1983) | 13,048 | 29 |
| Spectrum (2016) | 191,207 | 111 |
| The Spectrum Retreat (2018) | 1,475,771 | 2,038 |
| Spectrum Safari (1983) | 820 | 4 |
| Speculum Mortis (2007) | 218 | 2 |
| Speebot (2017) | 3,509 | 23 |
| Speed 3: Grand Prix (2020) | 297,672 | 211 |
| Speed Brawl (2018) | 976,023 | 941 |
| Speed Busters (1998) | 373,635 | 275 |
| Speed Busters: American Highways (1998) | 33,286 | 55 |
| Speed Car Fighter (2018) | 976 | 14 |
| Speed Challenge: Jacques Villeneuve's Racing Vision (2002) | 95,836 | 32 |
| Speed Dating for Ghosts (2018) | 1,748,687 | 426 |
| Speed Demons (1999) | 13,803 | 8 |
| Speed Demons (2019) | 10,158 | 28 |
| Speed Freak (1979) | 14,000 | 21 |
| Speed Freaks (1999) | 677,741 | 389 |
| Speed Haste (1995) | 41,172 | 25 |
| Speed is Key (2023) | 3,704 | 21 |
| Speed Kills (2014) | 357,879 | 215 |
| Speed Kings (2003) | 1,118,991 | 390 |
| Speed Limit (2021) | 1,179,730 | 752 |
| Speed Mazing (2021) | 1,252 | 8 |
| Speed Power Gunbike (1998) | 82,101 | 69 |
| Speed Race (1974) | 36,140,496 | 1,133 |
| Speed Race Twin (1976) | 93 | 2 |
| Speed Racer (1995) | 261,099 | 36 |
| Speed Racer (1996) | 301,936 | 69 |
| Speed Racer in My Most Dangerous Adventures (1994) | 52,688 | 58 |
| Speed Racer in The Challenge of Racer X (1992) | 61,042 | 11 |
| Speed Racer: The Videogame (2008) | 3,469,078 | 3,406 |
| Speed Racing Ultimate (2013) | 165,987 | 111 |
| Speed Rumbler (1986) | 338,866 | 113 |
| Speed Truck Racing (2021) | 11,859 | 41 |
| Speed Witch Battle: White Witch and Five Hopes (2018) | 60,841 | 6 |
| Speed Zone (1988) | 101,566 | 124 |
| Speedball (1988) | 1,333,867 | 545 |
| Speedball 2 Tournament (2007) | 137,990 | 18 |
| Speedball 2100 (2000) | 52,068 | 74 |
| Speedball 2: Brutal Deluxe (1990) | 1,425,958 | 466 |
| Speedball 2: Evolution (2011) | 117,590 | 60 |
| Speedboat Assassins (1989) | 1,923 | 11 |
