| Scratch Girl (2021) | 1,659 | 2 |
| Scratches (2006) | 128,278,985 | 6,679 |
| Scream Go Hero (2017) | 34,765,394 | 589 |
| ScreamCap (2021) | 132 | 2 |
| Screamer (1995) | 10,722,900 | 1,247 |
| Screamer 2 (1996) | 172,117 | 172 |
| Screamer 4x4 (2000) | 49,692 | 54 |
| Screamer Rally (1997) | 38,291 | 55 |
| Screaming Chicken: Ultimate Showdown (2023) | 2,946,795 | 108 |
| Screaming Eagles (2017) | 12,777,976 | 100 |
| Screaming Loaf (2022) | 1,791 | 9 |
| Screaming Wings (1986) | 13,697 | 33 |
| Screamride (2015) | 11,151,214 | 919 |
| Screech (2025) | 3,641,306 | 184 |
| Screencheat (2014) | 24,029,900 | 1,137 |
| Screeps: Arena (2022) | 3,804 | 30 |
| Screeps: World (2016) | 716,399 | 33 |
| Screw Drivers (2024) | 12,185,660 | 1,216 |
| Screwjumper! (2007) | 5,498 | 6 |
| ScrewUp (2021) | 273,852 | 126 |
| Scribble It! (2020) | 56,474,726 | 1,634 |
| Scribble Space (2015) | 5,051 | 8 |
| Scribbled (2021) | 30,174 | 18 |
| Scribblenauts (2009) | 113,102,388 | 2,259 |
| Scribblenauts Remix (2011) | 3,775,916 | 239 |
| Scribblenauts Unlimited (2012) | 377,583,150 | 14,283 |
| Scribblenauts Unmasked: A DC Comics Adventure (2013) | 88,190,218 | 2,174 |
| Scribblenauts: Mega Pack (2018) | 941,389 | 255 |
| Scribblenauts: Showdown (2018) | 14,810,121 | 555 |
| Scribe (2024) | 209,927 | 69 |
| Scripted Land (2024) | 0 | 0 |
| The Scroll Of Taiwu (2018) | 910,137 | 571 |
| Scrolling Walls (1988) | 351 | 3 |
| Scrollonoid (2017) | 0 | 0 |
| The Scrolls of Abadon (1984) | 648 | 6 |
| Scrolls of Sengoku Dynasty (2022) | 3,932 | 3 |
| Scroter (2023) | 0 | 0 |
| The Scruffs: Return of the Duke (2012) | 3,370 | 13 |
| ScrumbleShip (2011) | 86,383 | 42 |
| The Scrungeon Depths (2017) | 0 | 0 |
| Scrunk (2018) | 2,591 | 4 |
| Scrutinized (2020) | 91,147,217 | 1,354 |
| SCSIcide (2001) | 375 | 6 |
| Scuba Dive (1983) | 46,562 | 41 |
| ScubaVenture: The Search for Pirate's Treasure (1993) | 10,999 | 9 |
| Scud Atak (1991) | 495 | 2 |
| Scud Frenzy (2018) | 223 | 4 |
| Scud Race (1996) | 1,854,702 | 966 |
| Scud: The Disposable Assassin (1997) | 222,414 | 102 |
| Scuffle Scoundrels (2017) | 0 | 0 |
| Scufflers (2022) | 123 | 5 |
| SculptrVR (2016) | 4,773,604 | 155 |
| Scum (2018) | 522,765,807 | 112,276 |
| SCUOS (2019) | 0 | 0 |
| Scurge: Hive (2006) | 643,946 | 423 |
| Scurvy Dogs (2022) | 191,121 | 16 |
| Scutter (2018) | 2,066 | 4 |
| Scuttlers (2018) | 0 | 0 |
| Scythe: Digital Edition (2018) | 791,881 | 176 |
| SD Dungeons (2025) | 333 | 2 |
| SD F-1 Grand Prix (1995) | 46,441 | 88 |
| SD Gundam 2 (1993) | 2,935 | 10 |
| SD GUNDAM BATTLE ALLIANCE (2022) | 17,295,333 | 12,485 |
| SD Gundam Capsule Fighter Online (2011) | 11,436,509 | 8,399 |
| SD Gundam Daizukan (1994) | 316 | 1 |
| SD Gundam Dimension War (1995) | 46,711 | 30 |
| SD Gundam G Generation 3D (2011) | 1,038,693 | 102 |
| SD Gundam G Generation Advance (2003) | 301,469 | 161 |
| SD Gundam G Generation Cross Rays (2019) | 59,836,132 | 17,992 |
| SD Gundam G Generation DS (2005) | 496,935 | 120 |
| SD Gundam G Generation Frontier (2013) | 362,791 | 8 |
| SD Gundam G Generation Genesis (2016) | 23,953,107 | 5,719 |
| SD Gundam G Generation Neo (2002) | 410,188 | 477 |
| SD Gundam G Generation Overworld (2012) | 6,132,226 | 2,653 |
| SD Gundam G Generation Portable (2006) | 369,277 | 338 |
