| Screeps: World (2016) | 716,399 | 33 |
| Screw Drivers (2024) | 10,849,005 | 1,113 |
| Screwjumper! (2007) | 5,456 | 6 |
| ScrewUp (2021) | 273,851 | 126 |
| Scribble It! (2020) | 56,430,677 | 1,532 |
| Scribble Space (2015) | 5,051 | 8 |
| Scribbled (2021) | 29,561 | 13 |
| Scribblenauts (2009) | 112,924,167 | 2,207 |
| Scribblenauts Remix (2011) | 3,775,880 | 239 |
| Scribblenauts Unlimited (2012) | 377,455,110 | 14,018 |
| Scribblenauts Unmasked: A DC Comics Adventure (2013) | 88,141,012 | 2,148 |
| Scribblenauts: Mega Pack (2018) | 941,337 | 249 |
| Scribblenauts: Showdown (2018) | 14,805,493 | 520 |
| Scribe (2024) | 186,789 | 57 |
| Scripted Land (2024) | 0 | 0 |
| The Scroll Of Taiwu (2018) | 890,672 | 564 |
| Scrolling Walls (1988) | 351 | 3 |
| Scrollonoid (2017) | 0 | 0 |
| The Scrolls of Abadon (1984) | 648 | 6 |
| Scrolls of Sengoku Dynasty (2022) | 3,932 | 3 |
| Scroter (2023) | 0 | 0 |
| The Scruffs: Return of the Duke (2012) | 3,370 | 13 |
| ScrumbleShip (2011) | 86,383 | 42 |
| Scrunk (2018) | 2,591 | 4 |
| Scrutinized (2020) | 89,982,404 | 1,308 |
| SCSIcide (2001) | 375 | 6 |
| Scuba Dive (1983) | 46,562 | 41 |
| ScubaVenture: The Search for Pirate's Treasure (1993) | 10,999 | 9 |
| Scud Atak (1991) | 495 | 2 |
| Scud Frenzy (2018) | 223 | 4 |
| Scud Race (1996) | 1,838,345 | 939 |
| Scud: The Disposable Assassin (1997) | 222,228 | 100 |
| Scuffle Scoundrels (2017) | 0 | 0 |
| Scufflers (2022) | 123 | 5 |
| SculptrVR (2016) | 4,773,600 | 155 |
| Scum (2018) | 521,316,319 | 111,131 |
| SCUOS (2019) | 0 | 0 |
| Scurge: Hive (2006) | 510,980 | 389 |
| Scurvy Dogs (2022) | 190,982 | 15 |
| Scutter (2018) | 2,066 | 4 |
| Scuttlers (2018) | 0 | 0 |
| Scythe: Digital Edition (2018) | 791,863 | 176 |
| SD Dungeons (2025) | 333 | 2 |
| SD F-1 Grand Prix (1995) | 46,112 | 88 |
| SD Gundam 2 (1993) | 2,935 | 10 |
| SD GUNDAM BATTLE ALLIANCE (2022) | 17,281,441 | 12,404 |
| SD Gundam Capsule Fighter Online (2011) | 11,379,701 | 8,380 |
| SD Gundam Daizukan (1994) | 316 | 1 |
| SD Gundam Dimension War (1995) | 46,711 | 30 |
| SD Gundam G Generation 3D (2011) | 1,038,567 | 101 |
| SD Gundam G Generation Advance (2003) | 301,386 | 160 |
| SD Gundam G Generation Cross Rays (2019) | 58,243,259 | 17,821 |
| SD Gundam G Generation DS (2005) | 493,261 | 120 |
| SD Gundam G Generation Frontier (2013) | 362,791 | 8 |
| SD Gundam G Generation Genesis (2016) | 23,867,430 | 5,383 |
| SD Gundam G Generation Neo (2002) | 409,162 | 452 |
| SD Gundam G Generation Overworld (2012) | 6,115,605 | 2,627 |
| SD Gundam G Generation Portable (2006) | 368,313 | 327 |
| SD Gundam G Generation RE (2017) | 539,021 | 80 |
| SD Gundam G Generation Seed (2004) | 46,962 | 100 |
| SD Gundam G Generation Spirits (2007) | 824,313 | 279 |
| SD Gundam G Generation Wars (2009) | 4,753,471 | 973 |
| SD Gundam G Generation World (2011) | 1,131,713 | 526 |
| SD Gundam G Generation-F (2000) | 2,133,202 | 1,269 |
| SD Gundam G Generation: Monoeye Gundams (2002) | 192,384 | 54 |
| SD Gundam G Next (1995) | 591,794 | 62 |
| SD Gundam Gaiden: Knight Gundam Monogatari (1990) | 19,362 | 46 |
| SD Gundam Gaiden: Knight Gundam Monogatari 2 (1991) | 4,264 | 14 |
| SD Gundam Gaiden: Knight Gundam Monogatari 3 (1992) | 3,455 | 52 |
| SD Gundam Generation (1996) | 61,448 | 35 |
| SD Gundam GX (1994) | 435,525 | 136 |
| SD Gundam Neo Battling (1992) | 152,178 | 48 |
| SD Gundam Power Formation Puzzle (1996) | 38,748 | 26 |
| SD Gundam Strikers (2015) | 161,905 | 19 |
| SD Gundam World: Gachapon Senshi - Scramble Wars (1988) | 19,977 | 25 |
