| Sclash (2023) | 1,643,504 | 489 |
| Sclender (2022) | 0 | 0 |
| Scooby Doo 2 - Monsters Unleashed (2004) | 961,451 | 231 |
| Scooby Doo 2 Monsters Unleashed (2004) | 1,539,471 | 124 |
| Scooby Doo! Case File #3: Frights, Camera, Mystery! (2006) | 571,283 | 27 |
| Scooby Doo: The Motion Picture (2001) | 2,118 | 19 |
| Scooby-Doo (1986) | 49,784,398 | 927 |
| Scooby-Doo (2002) | 109,263 | 9 |
| Scooby-Doo and Scrappy-Doo (1991) | 111,820 | 110 |
| Scooby-Doo and the Cyber Chase (2001) | 10,187,421 | 2,286 |
| Scooby-Doo Case File #2: The Scary Stone Dragon (2003) | 430,435 | 43 |
| Scooby-Doo in the Castle Mystery (1986) | 12,044 | 5 |
| Scooby-Doo Mystery (1995) | 46,428,843 | 1,588 |
| Scooby-Doo Mystery Cases (2018) | 312,573 | 170 |
| Scooby-Doo! and the Spooky Swamp (2010) | 46,016,124 | 1,933 |
| Scooby-Doo! Classic Creep Capers (2000) | 6,481,134 | 579 |
| Scooby-Doo! First Frights (2009) | 81,769,766 | 4,734 |
| Scooby-Doo! Jinx at the Sphinx (2000) | 5,320,452 | 45 |
| Scooby-Doo! Mystery Adventures (2000) | 21,695 | 26 |
| Scooby-Doo! Mystery Mayhem (2003) | 25,585,718 | 1,993 |
| Scooby-Doo! Mystery of the Fun Park Phantom (1999) | 366,425 | 19 |
| Scooby-Doo! Night of 100 Frights (2002) | 9,432,895 | 4,593 |
| Scooby-Doo! Phantom of the Knight (2000) | 961,267 | 59 |
| Scooby-Doo! Showdown in Ghost Town (2000) | 846,052 | 72 |
| Scooby-Doo! Unmasked (2005) | 7,381,233 | 1,946 |
| Scooby-Doo! Who's Watching Who? (2006) | 1,454,390 | 229 |
| Scooby-Doo: Jinx at the Sphinx (2001) | 568,572 | 51 |
| Scooby-Doo: Phantom of the Knight (2000) | 58,364 | 74 |
| Scoot Scoot (2016) | 2,638,571 | 34 |
| Scooter Shooter (1985) | 39,767 | 40 |
| Scooter War3z (2006) | 18,779 | 16 |
| Scope X (2025) | 0 | 0 |
| SCOPECREEP (2026) | 0 | 0 |
| Scorched 3D (2001) | 84,683 | 27 |
| Scorched Planet (1996) | 15,488 | 17 |
| Scorched Tanks (1993) | 16,732 | 16 |
| Scorcher (1996) | 477,437 | 171 |
| The Scorchfarer (2022) | 631 | 25 |
| Scorchie Adventures (2026) | 0 | 0 |
| Scorching Desert (2025) | 103,099 | 26 |
| Scorchlands (2023) | 265,756 | 198 |
| Score 3020 (1988) | 4,664 | 11 |
| SCORE International Baja 1000 (2008) | 294,956 | 196 |
| Score Rush (2010) | 39,044 | 103 |
| Score! Classic Goals (2012) | 56,702 | 13 |
| Score! Hero (2015) | 153,376,516 | 11,126 |
| Scoregasm (2011) | 27,883 | 96 |
| Scorn (2022) | 401,597,307 | 28,878 |
| Scorphius (2022) | 57 | 1 |
| The Scorpion King: Rise of the Akkadian (2002) | 1,109,115 | 307 |
| The Scorpion King: Sword of Osiris (2002) | 246,935 | 145 |
| Scorpion Overdrive (2022) | 221 | 5 |
| Scorpion's Curse (2024) | 6,728 | 2 |
| Scorpion: Disfigured (2009) | 171,942 | 199 |
| Scorpius (1988) | 8,133 | 11 |
| Scorpius (1991) | 78,184 | 11 |
| Scotophobia (2024) | 1,592 | 13 |
| Scott in Space (2015) | 589,125 | 66 |
| Scott Pilgrim vs. the World: The Game (2010) | 37,949,081 | 12,676 |
| Scott Whiskers in: the Search for Mr. Fumbleclaw (2024) | 14,698 | 145 |
| Scott Whiskers: the Search for the Golden Cat (2025) | 0 | 0 |
| Scottside (2026) | 0 | 0 |
| Scourge of War: Gettysburg (2010) | 240,441 | 108 |
| The Scourge Project (2010) | 165,180 | 156 |
| Scourge: Outbreak (2013) | 1,549,817 | 786 |
| ScourgeBringer (2020) | 2,329,985 | 1,866 |
| The Scouring (2025) | 211 | 15 |
| SCP : A Star Replicator (2025) | 1,348 | 5 |
| SCP Strategy (2022) | 0 | 0 |
| SCP-087 (2012) | 12,071,346 | 772 |
| SCP-087-B (2012) | 48,046,268 | 1,984 |
| SCP: 5K (2022) | 16,865,553 | 1,770 |
| SCP: Blackout (2019) | 10,829,552 | 306 |
| SCP: Daybreak (2022) | 56,129 | 48 |
| SCP: Descent (2024) | 8,178,941 | 212 |
