| The Superlatives: Aetherfall (2017) | 4,886 | 1 |
| The Superlatives: Shattered Worlds (2019) | 3,106 | 1 |
| Superleague Formula 2009: The Game (2009) | 20,613 | 16 |
| Superliminal (2019) | 242,357,279 | 18,716 |
| Supermagical (2017) | 36,413 | 51 |
| Superman (1978) | 498,348 | 147 |
| Superman (1987) | 7,787,136 | 133 |
| Superman (1988) | 672,539 | 410 |
| Superman (1992) | 413,348 | 280 |
| Superman (1999) | 70,314,392 | 2,196 |
| Superman Returns (2006) | 168,271,405 | 2,678 |
| Superman Returns: Fortress of Solitude (2006) | 93,860 | 52 |
| Superman: Countdown to Apokolips (2003) | 36,812 | 62 |
| Superman: Shadow of Apokolips (2002) | 8,587,189 | 513 |
| Superman: The Game (1985) | 13,899,112 | 969 |
| Superman: The Man of Steel (1989) | 38,764 | 23 |
| Superman: The Man of Steel (2002) | 16,200,033 | 785 |
| Supermarket Mania (2008) | 410,294 | 417 |
| Supermarket Shriek (2019) | 2,190,563 | 423 |
| Supermarket Simulator (2024) | 420,350,836 | 65,414 |
| Supermarket Together (2024) | 5,989,529 | 4,007 |
| Supermarket Tycoon (2017) | 11,778 | 86 |
| SuperMash (2019) | 625,444 | 433 |
| SuperMoose (2016) | 3,196 | 10 |
| Supermoves (2024) | 500,070 | 80 |
| Supernatural Role Playing Game (2009) | 170,429 | 84 |
| Supernatural Shenanigans (2024) | 1,017 | 9 |
| Supernatural Super Squad Fight! (2019) | 2,613 | 11 |
| Supernova (1987) | 70,014 | 23 |
| Supernova Tactics (2022) | 31,754 | 43 |
| Superola Champion Edition (2022) | 51,933 | 97 |
| SuperPosition (2025) | 857,594 | 168 |
| SuperPower (2002) | 30,049,825 | 659 |
| SuperPower 2 (2004) | 3,860,620 | 829 |
| Superscout (2024) | 53,656 | 58 |
| Supersonic (2011) | 12,307,975 | 1,105 |
| Supersonic Acrobatic Rocket-Powered Battle-Cars (2008) | 7,019,503 | 1,155 |
| Supersonic Racers (1996) | 53,998 | 86 |
| Supersonic Tank Cats (2020) | 55 | 2 |
| SuperSpec Rallycross (2024) | 22,029 | 37 |
| Supersports: The Alternative Olympics (1988) | 640 | 4 |
| Superstar Chefs (2003) | 15,966 | 51 |
| Superstar Dance Club (2001) | 71,428 | 56 |
| Superstar Hero (2019) | 40,241 | 23 |
| Superstar Ice Hockey (1987) | 17,279 | 27 |
| Superstar IZ*ONE (2020) | 9,975 | 20 |
| Superstar Racing (2021) | 191,299 | 301 |
| SuperStar SMTOWN (2014) | 290,000 | 450 |
| Superstar Streetz (2022) | 43,922 | 144 |
| Superstars V8 Next Challenge (2010) | 657,721 | 238 |
| Superstars V8 Racing (2009) | 449,185 | 247 |
| Superstatic (2015) | 141,333 | 11 |
| SuperTotalCarnage! (2022) | 30,922 | 53 |
| SUPERVERSE (2019) | 17,439 | 33 |
| SUPERVOID (2024) | 3,449 | 2 |
| Supesu (2018) | 4 | 1 |
| Supesu 2 (2019) | 25,231 | 25 |
| The Supper (2020) | 6,236,415 | 1,197 |
| The Supper: New Blood (2025) | 1,693,034 | 126 |
| Supplice (2023) | 475,922 | 588 |
| Supply Chain Idle (2018) | 44,613 | 27 |
| Suppress Academician (2024) | 398 | 4 |
| Supraball (2019) | 5,958,558 | 246 |
| Supraland (2019) | 153,460,868 | 9,457 |
| Supraland Six Inches Under (2022) | 33,403,222 | 2,996 |
| Supremacy 1914 (2009) | 6,721,991 | 5,602 |
| Supremacy MMA (2011) | 3,730,612 | 615 |
| Supremacy: Your Will Be Done (1990) | 82,625 | 141 |
| Supreme Commander (2007) | 63,730,681 | 20,467 |
| Supreme Commander 2 (2010) | 17,036,498 | 7,441 |
| Supreme Fighters (2024) | 19,173 | 14 |
| Supreme Ruler 1936 (2014) | 263,139 | 76 |
| Supreme Ruler 2010 (2005) | 44,184 | 18 |
| Supreme Ruler 2020 (2008) | 1,237,335 | 1,434 |
| Supreme Ruler 2020: Global Crisis (2009) | 27,339 | 11 |
