| Slay (1995) | 15,942,015 | 1,115 |
| Slay or Fall (2024) | 56,572 | 14 |
| Slay the Alice (2025) | 2,674 | 34 |
| Slay The Bigies (2020) | 1,264 | 1 |
| Slay The Dragon (2018) | 343 | 10 |
| Slay the Dragon! (2021) | 132,220 | 144 |
| Slay the Dragon! The Fire-Breathing Tyrant Meets Her Match! (2024) | 9 | 2 |
| Slay the Princess (2023) | 38,171,148 | 8,596 |
| Slay The Spire (2019) | 376,134,117 | 133,130 |
| Slay the Spire 2 (2025) | 49,221,832 | 9,949 |
| Slay Together (2019) | 92,323 | 82 |
| Slayaway Camp (2016) | 30,966,359 | 1,152 |
| Slayaway Camp 2 (2024) | 56,396 | 167 |
| Slayaway Camp: 1980's Horror Puzzle Fun! (2016) | 23,739 | 20 |
| Slayaway Camp: Butcher's Cut (2017) | 418,331 | 355 |
| Slaycation Paradise (2022) | 281,554 | 275 |
| Slayer (1988) | 40,544 | 34 |
| Slayer Of Sin (2022) | 0 | 0 |
| Slayers (1994) | 68,890,516 | 5,075 |
| SLAYERS FOR HIRE (2020) | 4,946 | 7 |
| Slayers Royal (1997) | 78,116 | 128 |
| Slayers Royal 2 (1998) | 81,601 | 147 |
| Slayers Wonderful (1998) | 38,888 | 62 |
| Slayers X: Terminal Aftermath: Vengance of the Slayer (2023) | 3,265,243 | 1,176 |
| Slaygon (1988) | 78 | 2 |
| Slayin 2 (2020) | 85,314 | 100 |
| Slayin DX (2024) | 915 | 7 |
| Sled Shred featuring the Jamaican bobsled team (2010) | 132,223 | 13 |
| Sled Storm (1999) | 754,005 | 582 |
| Sled Storm (2002) | 187,302 | 95 |
| Sledge Hammer (2012) | 10,379,735 | 428 |
| Sleembo (2024) | 76 | 3 |
| Sleep and Girls (2021) | 0 | 0 |
| SLEEP AWAKE (2025) | 2,180 | 10 |
| The Sleep Experiment (2023) | 0 | 0 |
| Sleep Is Death (2010) | 836 | 7 |
| Sleep Walk (2010) | 1,169,820 | 53 |
| Sleeper S9 (2025) | 0 | 0 |
| Sleeping Dogs (2012) | 554,257,149 | 140,839 |
| Sleeping Gods Lie (1989) | 10,571 | 21 |
| Sleeping Valley (2016) | 20,910 | 15 |
| Sleeping With Sakuya Izayoi (2024) | 26 | 1 |
| Sleeping: Counting Sheep (2024) | 0 | 0 |
| Sleepless Night (2012) | 496,018 | 193 |
| Sleepover Party (2010) | 46,920,031 | 197 |
| Sleepwalker (1993) | 8,268,649 | 512 |
| Sleepytime Village (2026) | 0 | 0 |
| Sleigh Strikers (2024) | 45 | 4 |
| SLEIGHT - Nerve Wracking Espionage Party Game (2022) | 24 | 1 |
| Slender Man's Shadow (2013) | 4,996,250 | 1,403 |
| Slender Rising (2013) | 12,122,678 | 367 |
| Slender Rising 2 (2014) | 1,675,710 | 115 |
| Slender Threads (2025) | 3,245,456 | 697 |
| Slender: The Arrival (2013) | 2,333,588,143 | 75,972 |
| Slender: The Eight Pages (2012) | 1,769,553,001 | 61,044 |
| SLG Remix (2016) | 54 | 1 |
| SLICE (2018) | 53,162,010 | 3,594 |
| Slice & Dice (2024) | 6,692,690 | 1,451 |
| Slice It Down (2024) | 0 | 0 |
| Slice It! (2010) | 67,609,983 | 26,022 |
| Slice of Life Fantasy (2022) | 2,542 | 13 |
| Slice of Sea (2021) | 178,416 | 181 |
| Slice, Dice & Rice (2017) | 601,179 | 204 |
| Slicks (1992) | 6,115,950 | 375 |
| Slide Adventure MAGKID (2007) | 15,991 | 17 |
| Slide Faster (2024) | 626 | 7 |
| Slide Stars (2022) | 78,114 | 159 |
| Slidemagi (2024) | 845 | 14 |
| SlideNGlide (2025) | 0 | 0 |
| Sliders (1991) | 1,373,108 | 220 |
| Sliding Bears (2024) | 120 | 8 |
| Sliding Heroes (2009) | 7,370 | 10 |
| Sliding Knight (2026) | 0 | 0 |
| Sliding Skill (1991) | 311 | 3 |
| Sliding Swords (2023) | 6,882 | 10 |
