| Spectacular Sparky (2021) | 374,333 | 171 |
| Spectacular Team: Assemble (2026) | 0 | 0 |
| Spectar (1980) | 10,374 | 29 |
| Spectator (2023) | 42,810,027 | 1,185 |
| Specters of the Deep (2025) | 0 | 0 |
| Specters of the Sun (2025) | 107 | 5 |
| Spectipede (1983) | 3,031 | 9 |
| Spectra (2015) | 1,946,968 | 276 |
| Spectraball (2008) | 45,531 | 168 |
| Spectral Climb (2024) | 0 | 0 |
| Spectral Force 3 (2006) | 158,263 | 228 |
| Spectral Force Chronicle (2005) | 24,740 | 7 |
| Spectral Force Genesis (2008) | 135,799 | 26 |
| Spectral Force Radical Elements (2004) | 4,931 | 5 |
| Spectral Gene (2007) | 12,266 | 32 |
| Spectral Prison (2025) | 0 | 0 |
| Spectral Scream (2024) | 3,037,656 | 203 |
| Spectral Souls: Resurrection of the Ethereal Empires (2005) | 278,778 | 186 |
| Spectral vs. Generation (2005) | 656,262 | 528 |
| The Spectral Web: Hitodama (2023) | 173 | 39 |
| Spectre (1982) | 81,540,165 | 5 |
| Spectre (1991) | 3,708,935 | 255 |
| Spectre Divide (2024) | 7,033,349 | 2,689 |
| The Spectre Files: Deathstalker (2020) | 375,253 | 50 |
| Spectrewoods (2019) | 417,460 | 477 |
| Spectrobes (2007) | 2,099,214 | 913 |
| Spectrobes: Beyond the Portals (2008) | 746,469 | 423 |
| Spectrobes: Origins (2009) | 5,504,749 | 1,453 |
| Spectrolite (2021) | 7,812 | 62 |
| Spectromancer (2009) | 143,269 | 151 |
| Spectron (1983) | 9,949 | 27 |
| Spectrum (2016) | 913,706 | 197 |
| Spectrum Break (2018) | 0 | 0 |
| The Spectrum Retreat (2018) | 1,471,590 | 2,038 |
| Spectrum Safari (1983) | 818 | 3 |
| Spectrum Siege (2025) | 0 | 0 |
| Speculum Mortis (2007) | 218 | 2 |
| Speebot (2017) | 3,515 | 24 |
| Speed 3: Grand Prix (2020) | 252,612 | 187 |
| Speed Brawl (2018) | 955,109 | 927 |
| Speed Busters (1998) | 349,776 | 264 |
| Speed Busters: American Highways (1998) | 38,153 | 57 |
| Speed Car Fighter (2018) | 976 | 14 |
| Speed Challenge: Jacques Villeneuve's Racing Vision (2002) | 73,632 | 49 |
| Speed Crew (2024) | 610,070 | 302 |
| Speed Dating for Ghosts (2018) | 9,148,325 | 506 |
| Speed Demons (1999) | 33,415 | 14 |
| Speed Demons (2019) | 6,203 | 26 |
| Speed Demons 2 (2025) | 4 | 1 |
| Speed Freak (1979) | 16,099 | 26 |
| Speed Freaks (1999) | 672,361 | 366 |
| Speed Haste (1995) | 35,510 | 32 |
| Speed is Key (2023) | 1,690,642 | 66 |
| Speed Kills (2014) | 1,098,508 | 157 |
| Speed Kings (2003) | 531,890 | 312 |
| Speed Limit (2021) | 4,064,733 | 661 |
| Speed Mazing (2021) | 1,333 | 12 |
| Speed Power Gunbike (1998) | 133,896 | 76 |
| Speed Race (1974) | 58,375,358 | 1,498 |
| Speed Race Twin (1976) | 23 | 1 |
| Speed Racer (1995) | 5,859,191 | 555 |
| Speed Racer (1996) | 275,751 | 71 |
| Speed Racer in My Most Dangerous Adventures (1994) | 157,583 | 80 |
| Speed Racer in The Challenge of Racer X (1992) | 50,134 | 10 |
| Speed Racer: The Videogame (2008) | 3,265,692 | 4,784 |
| Speed Racing Ultimate (2013) | 108,186 | 94 |
| Speed Rumbler (1986) | 189,743 | 141 |
| Speed Truck Racing (2021) | 8,762 | 44 |
| Speed Witch Battle: White Witch and Five Hopes (2018) | 61,509 | 8 |
| Speed Zone (1988) | 534,068 | 73 |
| Speedball (1988) | 1,785,583 | 320 |
| Speedball 2 Tournament (2007) | 41,674 | 6 |
| Speedball 2100 (2000) | 50,191 | 65 |
| Speedball 2: Brutal Deluxe (1990) | 5,336,225 | 3,354 |
| Speedball 2: Evolution (2011) | 93,346 | 48 |
