| Submachine 3: The Loop (2006) | 15,326 | 52 |
| Submachine 4: The Lab (2007) | 119,307 | 65 |
| Submachine 5: The Root (2008) | 50,537 | 46 |
| Submachine 7: The Core (2010) | 372,268 | 41 |
| Submachine 8: The Plan (2012) | 120,089 | 38 |
| Submachine 9: The Temple (2014) | 192,475 | 56 |
| Submarine (1978) | 28,471 | 21 |
| Submarine Attack (1990) | 139,781 | 230 |
| Submarine Commander (1982) | 4,292,436 | 147 |
| Submarine Survivor (2024) | 4,496 | 43 |
| Submarine Terror (2024) | 41,095 | 9 |
| Submarine Titans (2000) | 597,190 | 413 |
| SubmarineS (2002) | 16,791,833 | 158 |
| Submerged (2015) | 8,992,860 | 3,477 |
| Submerged: Hidden Depths (2020) | 1,694,641 | 3,562 |
| Submergent (2024) | 130 | 3 |
| Subnautica (2018) | 3,714,910,126 | 390,738 |
| Subnautica: Below Zero (2021) | 1,249,083,247 | 161,919 |
| SUBNET - Escape Room Adventure (2023) | 265,294 | 47 |
| Suborbital (2024) | 29,945 | 6 |
| SubRoc-3D (1982) | 35,354 | 36 |
| subROV : Underwater Discoveries (2022) | 29,416 | 51 |
| Subside (2024) | 414,896 | 184 |
| Subsideria (2018) | 20,132 | 5 |
| Subsistence (2016) | 58,150,309 | 50,083 |
| SubSpace (1997) | 799,345 | 324 |
| Subspace Continuum (2015) | 145 | 2 |
| Subspace Discovery (2023) | 399 | 5 |
| Substation (1995) | 209,752 | 70 |
| Subsunk (1985) | 1,462 | 7 |
| Subsurface Circular (2017) | 116,201 | 231 |
| Subtension (2023) | 9,810 | 1 |
| SubterAlien Rescue (2023) | 0 | 0 |
| Subterfuge (2015) | 203,792 | 75 |
| Subterrain (2016) | 1,075,133 | 1,337 |
| Subterrain: Mines of Titan (2024) | 359,555 | 303 |
| Subterranauts (2024) | 58,190 | 8 |
| Subterranean Animism (2008) | 61,560,746 | 5,275 |
| Subterranean Starfield (2013) | 1,282 | 18 |
| Subterror (2024) | 976,166 | 223 |
| Subtrade (1992) | 3,249 | 6 |
| Subverse (2024) | 7,224,529 | 434 |
| Subwar 2050 (1993) | 312,319 | 64 |
| Subway Scramble (2005) | 2,736 | 6 |
| Subway Surfers (2012) | 8,290,007,518 | 685,705 |
| Subway Vigilante (1989) | 45,440 | 18 |
| Success Story (2009) | 118,399,571 | 827 |
| SUCCESSOR OF THE KEY (2020) | 3,125 | 9 |
| Successor To Your Throne (2023) | 0 | 0 |
| Succubi's Trap Dungeon of Seduction (2022) | 0 | 0 |
| Succubus 2069 (2024) | 2,831 | 22 |
| Succubus Challenge (2025) | 0 | 0 |
| Succubus Dungeon (2024) | 130 | 3 |
| Succubus Girl Story (2022) | 6 | 2 |
| Succubus Heaven (2024) | 1,102 | 2 |
| Succubus Hotel (2020) | 180 | 1 |
| Succubus in Wonderland (2023) | 0 | 0 |
| Succubus Melnea (2023) | 870 | 1 |
| Succubus Puttel (2024) | 0 | 0 |
| Succubus Runa and the Erotic Dungeon (2021) | 501 | 4 |
| Succubus Summon (2023) | 0 | 0 |
| Succubus With Guns (2021) | 298,652 | 393 |
| Succubus's making lunch (2023) | 382 | 3 |
| Succuquest (2023) | 8,442 | 6 |
| SuchArt: Creative Space (2021) | 342,435 | 152 |
| SuchArt: Genius Artist Simulator (2021) | 12,762,928 | 1,384 |
| Sucker for Love: Date to Die For (2024) | 4,519,483 | 694 |
| Sucker for Love: First Date (2022) | 27,328,192 | 1,689 |
| Sudden Attack (2005) | 266,490,987 | 11,890 |
| Sudden Attack 2 (2016) | 16,445,393 | 605 |
| Sudden Market (2023) | 51,054 | 73 |
| Sudden Strike (2001) | 1,438,853 | 1,426 |
| Sudden Strike 2 (2002) | 653,793 | 814 |
| Sudden Strike 3: Arms for Victory (2008) | 1,010,924 | 332 |
| Sudden Strike 4 (2017) | 19,188,790 | 9,100 |
