| Super Skweek (1990) | 86,367 | 123 |
| Super Sky Arena (2016) | 89,225 | 11 |
| Super Slam Dunk (1993) | 704,824 | 113 |
| Super Slap Shot (1993) | 24,933 | 57 |
| Super Slime Arena (2018) | 1,510,448 | 39 |
| Super Smash Asteroids (2023) | 349 | 11 |
| Super Smash Bros. (1999) | 2,232,888,871 | 137,165 |
| Super Smash Bros. Brawl (2008) | 1,581,941,103 | 143,473 |
| Super Smash Bros. for Nintendo 3DS (2014) | 166,456,022 | 20,713 |
| Super Smash Bros. for Wii U (2014) | 3,744,784,676 | 514,602 |
| Super Smash Bros. Melee (2001) | 0 | 0 |
| Super Smash Bros. Ultimate (2018) | 23,234,045,163 | 2,007,906 |
| Super Smash Flash (2006) | 8,588,163 | 1,963 |
| Super Smash Flash 2 (2017) | 90,332,120 | 26,129 |
| Super Smash Land (2011) | 2,161,670 | 314 |
| Super Soccer (1991) | 7,824,105 | 3,179 |
| Super Soccer Blast (2019) | 312,671 | 576 |
| Super Soccer Blast: America vs Europe (2021) | 196,961 | 130 |
| Super Soccer Champ (1992) | 65,605 | 93 |
| Super Sol Standard (2023) | 122 | 5 |
| Super Solitaire (1994) | 13,813 | 107 |
| Super Sonic Racer (2011) | 122,663 | 41 |
| Super Soukoban (1993) | 43,286 | 30 |
| Super Space Club (2021) | 72,248 | 135 |
| Super Space Invaders '91 (1990) | 416,923 | 509 |
| Super Space Jump Man (2019) | 184 | 3 |
| Super Space Meltdown (2015) | 799 | 9 |
| Super Space Pug (2016) | 416 | 10 |
| Super Space Shooter Arena (2019) | 0 | 0 |
| Super Space Slayer 2 (2019) | 19,120 | 387 |
| Super Space Towers (2021) | 362 | 3 |
| Super Spacefortress Macross (1992) | 970,314 | 253 |
| Super Speed Machines (2007) | 1,610 | 11 |
| Super Speed Race (1977) | 576,104 | 57 |
| Super Speed Race V (1978) | 4,915 | 2 |
| Super Spike V'Ball (1989) | 615,742 | 462 |
| Super Spooky Subgame Spectacular (2023) | 110 | 6 |
| Super Sportmatchen (2018) | 973,829 | 66 |
| Super Sprint (1986) | 621,690 | 463 |
| The Super Spy (1990) | 22,498,921 | 459 |
| Super Spy Hunter (1991) | 1,825,359 | 863 |
| Super Spy Hunter (1992) | 129,035 | 79 |
| Super Spy Raccoon (2023) | 3,367 | 30 |
| Super Squad (2021) | 2,068,886 | 236 |
| Super Squash (2020) | 237 | 1 |
| Super Squidlit (2021) | 17,512 | 58 |
| Super Star Battle (2025) | 0 | 0 |
| Super Star Blast (2019) | 13,029 | 48 |
| Super Star Panda (2018) | 103 | 4 |
| Super Star Path (2015) | 54,962 | 94 |
| Super Star Shooter 16 (2020) | 3,817 | 30 |
| Super Star Soldier (1990) | 1,163,803 | 713 |
| Super Star Wars (1992) | 16,743,655 | 4,158 |
| Super Star Wars: Return of the Jedi (1994) | 4,044,973 | 1,153 |
| Super Star Wars: The Empire Strikes Back (1993) | 8,080,709 | 1,672 |
| Super Stardust (1994) | 735,015 | 781 |
| Super Stardust Delta (2012) | 1,213,217 | 263 |
| Super Stardust HD (2007) | 1,566,099 | 742 |
| Super Steampunk Pinball 2D (2018) | 5,124 | 19 |
| Super Stickman Golf (2011) | 10,339,934 | 683 |
| Super Stone Legacy (2017) | 9,339 | 12 |
| Super Strawberry Man (2018) | 0 | 0 |
| Super Street Basketball (1992) | 1,973 | 12 |
| Super Street Basketball 2 (1994) | 939 | 6 |
| Super Street: Racer (2019) | 1,080,015 | 161 |
| Super Street: The Game (2018) | 10,757,528 | 1,132 |
| Super Strike Eagle (1993) | 64,879 | 112 |
| Super Stuntman (1987) | 9,932 | 26 |
| Super Stupid Space Invaders (1997) | 4,575 | 3 |
| Super Sushi Roll (2023) | 312 | 5 |
| Super Swap (2010) | 2,767,150 | 20 |
| Super Swing Golf (2006) | 1,311,134 | 200 |
| Super Swing Golf: Season 2 (2007) | 182,982 | 112 |
| Super SWIV (1992) | 372,419 | 411 |
| Super TaeKwonDo Master (1996) | 12,470 | 8 |
