| Space Impossible (2016) | 336,758 | 170 |
| The Space in Between (2021) | 372,072 | 101 |
| Space industrial empire (2023) | 0 | 0 |
| Space Instigators (2003) | 628 | 8 |
| Space Interceptor (2004) | 67,328 | 68 |
| Space Intervention (2021) | 110,909 | 251 |
| Space Invaders (1978) | 12,247,626 | 5,142 |
| Space Invaders (1999) | 2,012 | 21 |
| Space Invaders (2002) | 49,388 | 92 |
| Space Invaders '95 (1995) | 25,567 | 103 |
| Space Invaders '95: The Attack of Lunar Loonies (1995) | 47,953 | 77 |
| Space Invaders 90 (1990) | 40,785 | 114 |
| Space Invaders Anniversary (2003) | 77,707 | 84 |
| Space Invaders DX (1993) | 106,103 | 164 |
| Space Invaders Evolution (2009) | 17,670 | 26 |
| Space Invaders Extreme (2008) | 644,580 | 524 |
| Space Invaders Extreme (2018) | 85,352 | 84 |
| Space Invaders Extreme 2 (2009) | 414,152 | 162 |
| Space Invaders Forever (2020) | 287,130 | 167 |
| Space Invaders Get Even (2008) | 82,365 | 45 |
| Space Invaders II (1980) | 15,537 | 34 |
| Space Invaders Infinity Gene (2008) | 351,652 | 190 |
| Space Invaders Infinity Gene (2009) | 427,591 | 164 |
| Space Invaders Invincible Collection (2020) | 118,402 | 120 |
| Space Invaders OpenGL (2003) | 4,713 | 6 |
| Space Invaders Part II (1979) | 601,866 | 170 |
| Space Invaders Pocket (2005) | 21,443 | 17 |
| Space Invaders Revolution (2005) | 40,922 | 74 |
| Space Invaders Virtual Collection (1995) | 26,708 | 39 |
| Space Invaders: Galaxy Beat (2005) | 5,174 | 4 |
| Space Invaders: The Original Game (1995) | 71,163 | 69 |
| Space Jam (1996) | 184,767,190 | 2,911 |
| Space Jam: A New Legacy - The Game (2021) | 1,417,891 | 579 |
| Space Jammers (2017) | 111,309 | 49 |
| Space Jockey (1982) | 710,107 | 89 |
| SPACE JUNK HEROES (2021) | 0 | 0 |
| Space Junk Patrol (2016) | 932 | 1 |
| Space Junkies (2019) | 7,549,415 | 1,145 |
| Space Kettle (2021) | 257,418 | 29 |
| Space Killer (2023) | 13,090 | 18 |
| Space Launcher (1979) | 17,205 | 54 |
| Space Legends: At the Edge of the Universe (2014) | 101,327 | 69 |
| Space Live - Advent of the Net Idols (2017) | 3,801 | 9 |
| Space Love Delta (2020) | 25,806 | 21 |
| Space M+A+X (1986) | 160 | 1 |
| Space Mages: Dimension 33 (2021) | 0 | 0 |
| Space Major Miner (2022) | 1,684 | 2 |
| Space Manbow (1989) | 512,354 | 231 |
| Space Marmalade (2023) | 37 | 1 |
| Space Marshals (2015) | 837,453 | 1,137 |
| Space Marshals 2 (2016) | 4,182,393 | 1,262 |
| Space Mash (2025) | 0 | 0 |
| Space Mavericks (2022) | 2,269 | 13 |
| Space Maxwell: Arcade (2022) | 0 | 0 |
| Space Mayhem (2019) | 2,793 | 17 |
| Space Maze (2018) | 224,736 | 46 |
| Space Mechanic Simulator (2023) | 149,255 | 220 |
| Space Mega Force Man (2020) | 0 | 0 |
| Space Megaforce (1992) | 726,872 | 933 |
| Space Memory: Animals (2024) | 0 | 0 |
| Space Memory: Cats (2024) | 0 | 0 |
| Space Memory: Dogs (2024) | 0 | 0 |
| Space Menace (2022) | 7,147 | 55 |
| Space Menace 2 (2025) | 4,161 | 21 |
| Space Mercenary Defense Force (2022) | 6,696 | 52 |
| Space Merchant (2021) | 229 | 3 |
| Space Merchants: Arena (2016) | 2,829 | 3 |
| Space Mercs (2019) | 16,651 | 34 |
| Space Miner: Space Ore Bust (2010) | 22,201 | 31 |
| SPACE MOLMAE (2022) | 65 | 1 |
| Space Monkeys (2022) | 345,370 | 71 |
| Space Monster (1980) | 46,285 | 32 |
| Space Monster (2020) | 8 | 1 |
| Space Moonshiner (2022) | 188 | 2 |
| Space Moth DX (2016) | 26,185 | 63 |
