| Seer's Gambit (2024) | 102,383 | 50 |
| Seers Isle (2018) | 44,684 | 132 |
| Sees Game (2023) | 0 | 0 |
| Sefirot Shards (2022) | 3,709 | 47 |
| Sega 3D Classics Collection (2015) | 324,216 | 98 |
| Sega 3D Fukkoku Archives (2014) | 112,108 | 27 |
| Sega Arcade Gallery (2003) | 674,257 | 229 |
| Sega Bass Fishing (1997) | 5,794,482 | 1,608 |
| Sega Bass Fishing 2 (2001) | 53,627 | 21 |
| Sega Bass Fishing Duel (2002) | 75,996 | 10 |
| Sega Boku Doraemon (2001) | 7,183 | 1 |
| Sega Casino (2005) | 8,955 | 20 |
| Sega Dreamcast Web Browser (1999) | 1,005,480 | 20 |
| Sega Extreme Sports (2000) | 28,311 | 33 |
| SEGA Flipper (1983) | 93,219 | 31 |
| Sega Game Pack 4 in 1 (1992) | 22,592 | 57 |
| Sega Genesis Collection (2006) | 2,715,494 | 1,584 |
| Sega GT (2000) | 1,009,845 | 714 |
| Sega GT 2002 (2002) | 1,432,839 | 1,484 |
| Sega GT 2002 / Jet Set Radio Future (2002) | 56,375 | 8 |
| Sega GT Online (2004) | 130,140 | 194 |
| SEGA Heroes (2018) | 2,929,296 | 1,065 |
| Sega Marine Fishing (1999) | 651,570 | 136 |
| Sega Mega Drive Classic Collection (2010) | 9,773,279 | 6,000 |
| Sega NET Mahjong MJ (2013) | 9,047,400 | 5,061 |
| Sega Network Taisen Mahjong MJ4 (2008) | 452,469 | 119 |
| Sega Network Taisen Mahjong MJ5 (2011) | 340,662 | 170 |
| Sega Ninja (1985) | 566,608 | 352 |
| Sega Race TV (2008) | 269,298 | 119 |
| Sega Rally 2 (1998) | 4,466,877 | 1,700 |
| Sega Rally 2006 (2006) | 589,413 | 288 |
| Sega Rally 3 (2008) | 718,038 | 339 |
| Sega Rally Championship (1994) | 6,652,047 | 2,895 |
| Sega Rally Online Arcade (2011) | 185,074 | 167 |
| Sega Rally Revo (2007) | 4,025,799 | 2,613 |
| Sega Ski Super G (1996) | 116,003 | 63 |
| Sega Smash Pack (2002) | 110,383 | 75 |
| Sega Smash Pack 2 (2000) | 14,813 | 8 |
| Sega Soccer Slam (2002) | 2,228,143 | 445 |
| Sega Superstars (2004) | 873,369 | 143 |
| Sega Superstars Tennis (2008) | 6,032,379 | 2,226 |
| Sega Swirl (1999) | 99,158 | 35 |
| Sega Touring Car Championship (1996) | 756,336 | 331 |
| Sega Water Ski (1997) | 147,737 | 60 |
| Sega World Tournament Golf (1993) | 4,518 | 31 |
| Sega Worldwide Soccer '98 (1997) | 96,101 | 108 |
| Sega Worldwide Soccer 97 (1996) | 209,242 | 159 |
| Sega Worldwide Soccer PC (1995) | 5,820 | 12 |
| Segagaga (2001) | 2,258,444 | 343 |
| SegaSonic Cosmo Fighter (1993) | 209,590 | 96 |
| SegaSonic Popcorn Shop (1993) | 1,415,464 | 69 |
| SegaSonic the Hedgehog (1993) | 9,812,408 | 866 |
| Seibu Cup Soccer (1992) | 1,346,297 | 169 |
| Seicross (1984) | 392,249 | 246 |
| SEIDEN (2024) | 0 | 0 |
| Seifuku Densetsu: Pretty Fighter (1994) | 493,639 | 229 |
| Seifuku Kanojo (2024) | 11,622 | 5 |
| Seiken Densetsu 3 (1995) | 4,109,468 | 4,454 |
| Seiken Densetsu: Rise of Mana (2014) | 924,369 | 77 |
| Seiken Psycho Calibur: Maju no Mori Densetsu (1987) | 574 | 2 |
| Seikimatsu Days: Our Era's End (2018) | 241,748 | 62 |
| Seiklus (2003) | 19,922 | 18 |
| Seinarukana -The Spirit of Eternity Sword 2 (2017) | 49,520 | 181 |
| Seirei Gari (1989) | 228,199 | 45 |
| Seirei Senshi Spriggan (1991) | 98,892 | 163 |
| Seireishin Seiki Fhey Area (1992) | 54,545 | 65 |
| Seisen Cerberus (2011) | 999,654 | 29 |
| Seishin Destiny (2021) | 180 | 5 |
| Seiya Monogatari: Anearth Fantasy Stories (1995) | 6,314 | 23 |
| SeizureDome (2008) | 29 | 1 |
| The Sekimeiya: Spun Glass (2021) | 22,752 | 147 |
| Sekira (2026) | 0 | 0 |
| Sekiro: Shadows Die Twice (2019) | 2,064,104,568 | 587,361 |
| SEKISAI puzzle action (2023) | 1,069 | 10 |
| Sekrets Of The Dungeon (2024) | 0 | 0 |
