| Sherlock Holmes Chapter One (2021) | 14,383,830 | 14,858 |
| Sherlock Holmes Versus Jack the Ripper (2009) | 5,831,538 | 4,725 |
| Sherlock Holmes – The Hunt for Moriarty (2024) | 0 | 0 |
| Sherlock Holmes: Consulting Detective (1991) | 1,682,617 | 550 |
| Sherlock Holmes: Consulting Detective Vol. II (1992) | 19,806 | 44 |
| Sherlock Holmes: Consulting Detective Vol. III (1993) | 712 | 11 |
| Sherlock Holmes: Crimes and Punishments (2014) | 17,083,694 | 13,448 |
| Sherlock Holmes: The Awakened (2007) | 6,572,036 | 8,817 |
| Sherlock Holmes: The Case of the Silver Earring (2004) | 245,662 | 583 |
| Sherlock Holmes: The Devil's Daughter (2016) | 44,267,337 | 17,434 |
| Sherlock Holmes: The Mystery of the Mummy (2002) | 577,176 | 363 |
| Sherlock Holmes: The Mystery of the Persian Carpet (2008) | 74,080 | 105 |
| SherLock: Escape Room Adventure (2023) | 19 | 2 |
| Sherlock: The Riddle of the Crown Jewels (1987) | 6,831 | 7 |
| Sherman M4 (1989) | 22,276 | 20 |
| Sherwood (1992) | 7,816,034 | 636 |
| Sherwood Extreme (2021) | 532,917 | 284 |
| Shh! This is a mystery game! But watch out for spoilers (2023) | 4,087 | 4 |
| Shi Shi Shindoro Mu (2002) | 3,334 | 1 |
| Shiba Army (2022) | 13,454 | 4 |
| The Shield (2007) | 38,014,893 | 669 |
| Shield Shock (2020) | 31,035 | 21 |
| Shields of Asgard (2023) | 124 | 3 |
| Shields of Loyalty (2021) | 202,801 | 66 |
| Shieldwall (2020) | 145,009,972 | 3,690 |
| Shieldwall Chronicles: Swords of the North (2018) | 60,464 | 30 |
| Shien's Revenge (1994) | 47,790 | 84 |
| Shienryu (1997) | 363,188 | 250 |
| Shift (2008) | 1,447,599 | 136 |
| Shift 2 (2008) | 630,746 | 103 |
| Shift 2: Unleashed (2011) | 7,614,285 | 1,856 |
| Shift 3 (2008) | 228,010 | 28 |
| Shift 87 (2024) | 1,029,430 | 178 |
| Shift Happens (2015) | 34,933,576 | 2,277 |
| Shift Quantum (2018) | 868,617 | 219 |
| Shifters (2002) | 60,181,002 | 2,266 |
| Shifting World (2012) | 68,712 | 68 |
| Shiftlings (2015) | 957,946 | 276 |
| Shiftlings (2018) | 20,163 | 25 |
| Shiftrix (1991) | 861 | 3 |
| Shigeru Mizuki no Youkai Hyakkiyakou (1995) | 0 | 0 |
| Shigetaka Kashiwagi's Top Water Bassing (1995) | 732 | 5 |
| Shiju Hachi (2007) | 16,768,873 | 1,001 |
| Shikaku Shapes (2020) | 1,214 | 24 |
| Shikhondo - Soul Eater (2017) | 182,438 | 328 |
| Shikhondo: Youkai Rampage (2024) | 21,473 | 73 |
| Shiki-Tei (2008) | 3,216 | 5 |
| Shikon-X Astro Defense Fortress (2022) | 6,561 | 34 |
| Shillelagh (2021) | 12,788 | 27 |
| Shima Nagame (2014) | 20,498 | 3 |
| Shimano Xtreme Fishing (2009) | 452,757 | 30 |
| SHIMAZU (2023) | 436,336 | 102 |
| Shimono Masaki no Fishing to Bassing (1994) | 1,405 | 13 |
| Shin 4-Jin Uchi Mahjong: Yakuman Tengoku (1991) | 30,996 | 70 |
| Shin 4nin Uchi Mahjong: Yakuman Tengoku (1991) | 110 | 2 |
| Shin Galaxy - Engage (2023) | 72 | 1 |
| Shin Gouketsuji Ichizoku: Bonnou no Kaihou (2006) | 41,574 | 30 |
| Shin Ikkaku Senkin (1995) | 141 | 7 |
| Shin Lucky Star Moe Drill: Tabidachi (2007) | 3,904 | 2 |
| Shin Mahjong (1994) | 2,294 | 6 |
| Shin Megami Tensei (1992) | 27,339,747 | 16,733 |
| Shin Megami Tensei If... (1994) | 11,194,438 | 2,149 |
| Shin Megami Tensei II (1994) | 8,592,596 | 3,347 |
| Shin Megami Tensei III: Nocturne (2003) | 80,506,302 | 43,104 |
| Shin Megami Tensei IV (2013) | 29,536,758 | 7,029 |
| Shin Megami Tensei IV: Apocalypse (2016) | 18,644,556 | 4,223 |
| Shin Megami Tensei Trading Card: Card Summoner (2001) | 7,487 | 11 |
| Shin Megami Tensei V (2021) | 128,177,328 | 55,234 |
| Shin Megami Tensei: Devil Children - Puzzle de Call (2003) | 2,614 | 19 |
| Shin Megami Tensei: Devil Children Book of Fire/Book of Ice (2003) | 32,086 | 114 |
| Shin Megami Tensei: Devil Children: Black Book/Red Book (2000) | 426,080 | 440 |
| Shin Megami Tensei: Devil Summoner (1995) | 4,020,774 | 1,566 |
| Shin Megami Tensei: Devil Survivor (2009) | 6,143,317 | 2,314 |
| Shin Megami Tensei: Devil Survivor 2 (2011) | 2,684,026 | 1,755 |
| Shin Megami Tensei: Devil Survivor 2 Record Breaker (2015) | 5,404,349 | 1,599 |
