| South Park: Tenorman's Revenge (2012) | 1,981,765 | 266 |
| South Park: The Fractured but Whole (2017) | 723,351,218 | 92,774 |
| South Park: The Stick of Truth (2014) | 1,079,218,434 | 106,669 |
| South Pole Bebop (2024) | 550 | 10 |
| Southern Belle (1985) | 338,945 | 37 |
| Southern Princesses (2022) | 0 | 0 |
| Souvenir (2012) | 26,192,948 | 622 |
| Sovereign Elect (2024) | 18 | 1 |
| Sovereign Syndicate (2024) | 723,331 | 635 |
| Sovereign Tea (2021) | 5,204 | 30 |
| Sovereign's Will (2023) | 3,830 | 7 |
| Soviet (1990) | 10,803,669 | 871 |
| Soviet Jump Game (2020) | 374,839,413 | 1,152 |
| Soviet Soldier (2024) | 264,417 | 39 |
| SOVIET SPOOKY TALES: Green Eyes (2025) | 3,886 | 7 |
| Soviet Strike (1996) | 771,039 | 398 |
| SOVL (2023) | 1,259,305 | 599 |
| Sovranti (2023) | 3,413 | 19 |
| Sp!ng (2021) | 38,130 | 429 |
| Spa Mania (2016) | 17,685 | 19 |
| Spa Mania 2 (2016) | 25,909 | 12 |
| Space 'n Lasers (2021) | 31 | 2 |
| Space - The Return Of The Pixxelfrazzer (2015) | 1,991 | 7 |
| SPACE / MECH / PILOT (2020) | 1,257 | 10 |
| Space Abyss (2020) | 630 | 10 |
| SPACE ACCIDENT (2022) | 12,941 | 30 |
| Space Accident VR (2024) | 14 | 2 |
| Space Ace (1983) | 17,619,923 | 818 |
| Space Ace II: Borf's Revenge (1991) | 65,576 | 14 |
| Space Aces (2022) | 70,953 | 55 |
| Space Action (1983) | 151,919 | 51 |
| The Space Adventure (1991) | 23,058,191 | 407 |
| Space Adventure - Escape from Siphilus 1b (2022) | 0 | 0 |
| Space Adventure Cobra - The Awakening (2025) | 522 | 7 |
| Space Adventure TD (2019) | 26 | 1 |
| Space Adventures (2021) | 36,451,664 | 220 |
| Space Agent: 8 Artifacts (2021) | 0 | 0 |
| Space Aliens Invaders (2020) | 7,287 | 14 |
| Space Ape (2021) | 142,880 | 28 |
| Space Architect (2020) | 78,981 | 125 |
| Space Ark (2010) | 29,682 | 52 |
| Space Assistance (2022) | 0 | 0 |
| Space Avenger – Empire of Nexx (2020) | 0 | 0 |
| Space Avengers (2020) | 180,444 | 54 |
| Space Badminton VR (2016) | 0 | 0 |
| Space Ballers (2022) | 197 | 3 |
| Space Bandit (2022) | 5,151 | 20 |
| SPACE BANDITOS (2021) | 14,136 | 3 |
| The Space Bar (1997) | 3,389,850 | 391 |
| Space Bar at the End of the Galaxy (2020) | 269 | 1 |
| Space Base Defense (2025) | 0 | 0 |
| Space Battle (1979) | 1,366,538 | 445 |
| Space Battle Arena (2020) | 144 | 3 |
| Space Battle Royale (2023) | 25,800 | 32 |
| Space Battle SVF (2021) | 0 | 0 |
| SPACE BATTLE: Humanity (2017) | 0 | 0 |
| Space Battlecruiser (2018) | 3,425 | 10 |
| Space Battleship Yamato (1999) | 13,743,338 | 768 |
| Space Beast Terror Fright (2015) | 506,410 | 282 |
| Space Beast Terror Fright (2022) | 264,437 | 245 |
| Space Beastz (2022) | 0 | 0 |
| Space Bees 太空蜜蜂 (2022) | 4,626 | 11 |
| Space Beret (2016) | 2,880 | 6 |
| Space Betrayers (2022) | 1,234 | 1 |
| Space Between Worlds (2018) | 21,498 | 29 |
| Space Bit Attack (2016) | 2,719 | 8 |
| Space Blast Zom: A Matching Game (2021) | 654 | 3 |
| Space Blaze (2017) | 26,797 | 27 |
| Space Block Buster (2019) | 9,847 | 23 |
| Space BloX (2019) | 2,628 | 2 |
| Space Bob vs. The Replicons (2018) | 109,819 | 14 |
| Space Bomb (2019) | 274 | 5 |
| Space Bomber (1998) | 71,691 | 94 |
| Space Bound (2019) | 1,444,799 | 25 |
| Space Box Battle Arena (2022) | 20 | 2 |
