| Samurai Warriors 2 (2006) | 19,137,899 | 11,094 |
| Samurai Warriors 3 (2009) | 17,970,769 | 5,606 |
| Samurai Warriors 4 (2014) | 56,621,025 | 22,692 |
| Samurai Warriors 5 (2021) | 21,373,467 | 23,743 |
| Samurai Warriors Chronicles 2nd (2012) | 18,634 | 7 |
| Samurai Warriors Chronicles 3 (2014) | 625,636 | 364 |
| Samurai Warriors: Chronicles (2011) | 1,451,310 | 623 |
| Samurai Warriors: Chronicles 2nd (2012) | 2,962 | 3 |
| Samurai Warriors: Katana (2007) | 267,256 | 171 |
| Samurai Warriors: Sanada Maru (2016) | 264,778 | 97 |
| Samurai Warriors: Spirit of Sanada (2016) | 5,058,061 | 4,212 |
| Samurai Warriors: State of War (2005) | 3,812 | 15 |
| Samurai Western (2005) | 1,035,641 | 702 |
| Samurai Wish (2018) | 554 | 10 |
| Samurai-Ghost (1992) | 1,331,989 | 239 |
| Samurai: Way of the Warrior (2009) | 240,867 | 35 |
| SamuTale (2016) | 84,767 | 51 |
| SAMUZA (2024) | 3,628 | 16 |
| San Diego Zoo Presents: The Animals! (1992) | 9,755 | 22 |
| San Francisco Rush 2049 (1999) | 1,344,848 | 1,532 |
| San Francisco Rush: Extreme Racing (1996) | 1,933,042 | 1,030 |
| San Giorli (2017) | 3,591 | 3 |
| SANABI (2023) | 1,206,464 | 1,157 |
| Sanada Juu Yuushi (1988) | 7,433 | 12 |
| Sanae Toumaden X (2021) | 16,902 | 24 |
| SANAE's Sylphid Breeze (2025) | 0 | 0 |
| Sanalika (2008) | 1,440,384 | 101 |
| Sanator: Scarlet Scarf (2019) | 23,270 | 95 |
| Sancticide (2025) | 141,086 | 278 |
| Sanctuary in Time (2023) | 17 | 1 |
| Sanctuary Island (2022) | 665,491 | 38 |
| Sanctuary Saga (2023) | 53,482 | 58 |
| SanctuaryRPG (2014) | 298,119 | 363 |
| SanctuaryRPG: Black Edition (2015) | 85,866 | 142 |
| Sanctum (1998) | 808 | 13 |
| Sanctum (2011) | 7,240,973 | 1,886 |
| Sanctum 2 (2013) | 9,226,587 | 4,550 |
| Sanctum Arcadia (2023) | 188 | 8 |
| Sanctum Breach: Rebirth (2022) | 40,859 | 19 |
| Sanctum Protocol (2026) | 0 | 0 |
| Sanctus Mortem (2018) | 0 | 0 |
| SAND LAND (2024) | 7,636,405 | 7,030 |
| Sand: A Superfluous Game (2022) | 83,731 | 44 |
| The Sandbox (2012) | 635,880,129 | 24,979 |
| The Sandbox Evolution (2016) | 24,369,157 | 602 |
| The Sandbox of God (2004) | 56,072 | 6 |
| Sandbox:God Simulator (2023) | 59,541 | 19 |
| Sandmason (2015) | 3,788 | 13 |
| Sandra and Woo in the Cursed Adventure (2017) | 12,234 | 56 |
| Sandream (2022) | 4,319 | 17 |
| SANDRIPPER (2025) | 1,441 | 5 |
| Sands of Aura (2021) | 1,068,388 | 642 |
| Sands of Destruction (2008) | 786,953 | 537 |
| The Sands of Egypt (1982) | 4,942 | 20 |
| Sands of Fire (1989) | 791 | 3 |
| Sands of Salzaar (2021) | 3,647,474 | 1,402 |
| Sands of Skullcreek (2024) | 59 | 1 |
| Sands of Slumber: The RPG (2022) | 153 | 3 |
| Sandstorm (1992) | 22,255,737 | 1,090 |
| Sandstorm: Pirate Wars (2016) | 138,403 | 94 |
| SandTable War: Three Kingdoms (2026) | 298 | 1 |
| Sandustry (2026) | 0 | 0 |
| Sandwalkers (2025) | 0 | 0 |
| The Sandwich Making Experience (2023) | 0 | 1 |
| Sandy Beach (2009) | 379,061 | 191 |
| Sanfu (2023) | 447,979 | 186 |
| Sang-Froid: Tales of Werewolves (2013) | 1,643,582 | 1,166 |
| Sango Fighter (1993) | 690,751 | 192 |
| Sangoku Rush (2017) | 566 | 1 |
| Sangokushi Battlefield (2002) | 184 | 1 |
| Sangokushi Eiketsuden (1995) | 6,750,790 | 1,944 |
| Sangokushi Online (2008) | 60,103 | 14 |
| Sangokushi Seishi: Tenbu Spirits (1993) | 18,038 | 15 |
| Sangokushi Sousouden (1998) | 3,138,711 | 1,347 |
| Sangokushi Taisen (2005) | 13,603,915 | 12,473 |
