| Sealer Assist (2020) | 0 | 0 |
| Seals of the Bygone (2020) | 7,052 | 25 |
| Seaman (1999) | 24,200,709 | 1,295 |
| Seaman 2 (2007) | 1,798,542 | 309 |
| Seaquest (1983) | 405,708 | 269 |
| seaQuest DSV (1994) | 719,636 | 153 |
| The Search for Amelia Earhart (2010) | 5,733 | 10 |
| The Search For Paradisus (2022) | 1,967 | 9 |
| Search for the Golden Dolphin (1999) | 449 | 2 |
| Search for the Titanic (1989) | 0 | 0 |
| Search of Galaxy (2022) | 1,501 | 7 |
| The Searchers of Legends : Origin (2019) | 802 | 5 |
| Searching For Rest (2024) | 91,537 | 21 |
| Sears: The Sky Frontier (2023) | 390 | 9 |
| Seas of Blood (1985) | 193,106 | 62 |
| Seaside Cafe Rush Hour (2024) | 4,525 | 5 |
| Season of Mystery: The Cherry Blossom Murders (2010) | 13,387 | 55 |
| Season of War (Alpha) (2019) | 217 | 2 |
| SEASON: A letter to the future (2023) | 2,258,104 | 2,200 |
| Seasons (2004) | 1,919,223 | 12 |
| Seasons After Fall (2016) | 4,117,966 | 4,176 |
| Seasons of the Samurai (2020) | 6,458 | 28 |
| Seasons of the Sorcerer (2022) | 35 | 2 |
| Seasons With Furry (2020) | 162 | 1 |
| Seasonspree (2024) | 2,192 | 20 |
| Seastalker (1984) | 1,349 | 13 |
| Seasteader (2017) | 735,711 | 7 |
| Seaweed Assault (2011) | 948 | 4 |
| Seawolf (2004) | 21,134 | 28 |
| SeaWorld Adventure Parks Tycoon (2003) | 36,808 | 29 |
| SeaWorld Adventure Parks Tycoon 2 (2005) | 2,073 | 2 |
| Sébastien Loeb Rally Evo (2016) | 7,635,667 | 3,629 |
| Sebil Engineering (2023) | 2,128,686 | 31 |
| Sebio (2024) | 0 | 0 |
| Seclusa (2025) | 0 | 0 |
| Seclusion (2025) | 240,414 | 94 |
| Second Chance Heroes (2014) | 105,341 | 47 |
| Second Earth (2014) | 1,309,274 | 193 |
| Second Extinction (2020) | 25,531,542 | 6,756 |
| Second Front: Germany Turns East (1990) | 515 | 1 |
| Second Galaxy (2019) | 2,927,255 | 867 |
| The second guest (2012) | 52,083 | 122 |
| Second Hand: Frankie's Revenge (2019) | 295,474 | 59 |
| Second Life (2003) | 92,914,838 | 16,655 |
| Second Person: Secret Laboratory (2022) | 101,011 | 2 |
| Second Rate Superheroes (2024) | 3,427 | 11 |
| Second Room (2024) | 133,854 | 19 |
| Second Samurai (1993) | 433,915 | 277 |
| Second Second (2019) | 48,058 | 32 |
| Second Sight (2004) | 2,225,916 | 1,532 |
| Second Sun (2025) | 637,872 | 85 |
| Second World: Air War S (2018) | 214 | 2 |
| Seconds in Space (2020) | 36,234 | 8 |
| Secret Agent (1992) | 1,625,959 | 294 |
| Secret Agent (2001) | 54,017 | 30 |
| Secret Agent Barbie (2001) | 1,851,629 | 382 |
| Secret Agent Barbie: Royal Jewels Mission (2002) | 31,312 | 62 |
| Secret Agent Clank (2008) | 6,970,300 | 2,727 |
| Secret Agent Files: Miami (2013) | 6,713 | 2 |
| Secret Agent Wizard Boy and the International Crime Syndicate (2025) | 2,986,918 | 205 |
| Secret Agent: The Escape (1996) | 27,133 | 15 |
| The Secret Atelier (2024) | 10,662 | 4 |
| Secret Camera (2023) | 13,585,345 | 83 |
| Secret City: London Calling (2018) | 600,996 | 116 |
| Secret City: Mysterious Collection (2020) | 248,674 | 65 |
| Secret City: Sacred Fire (2021) | 229,729 | 55 |
| Secret City: The Chalk of Fate (2020) | 199,197 | 74 |
| Secret City: The Human Threat (2019) | 320,337 | 59 |
| Secret City: The Sunken City (2019) | 234,695 | 59 |
| The Secret Diary of Adrian Mole (1985) | 9,866 | 31 |
| Secret Dimension (2023) | 814,972 | 13 |
| Secret Files 2: Puritas Cordis (2008) | 2,516,687 | 2,089 |
| Secret Files 3 (2012) | 1,426,337 | 1,159 |
| Secret Files: Sam Peters (2013) | 476,200 | 435 |
| Secret Files: Tunguska (2006) | 14,820,479 | 4,257 |
